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Senior Bioinformatics Specialist

1 month ago

Stockport, Stockport, United Kingdom UK Biobank Limited Full time
About the Role

We are seeking a highly skilled Senior Bioinformatician to join our team at UK Biobank Limited. As a key member of our Data Management team, you will play a crucial role in leading the development and operationalisation of analytical pipelines and processes to manage large-scale multi-modal data.

Key Responsibilities
  • Lead the definition and refinement of the bioinformatics work backlog and oversee the associated planning and delivery.
  • Develop and maintain a strategy for bioinformatics at UK Biobank, defining appropriate skillsets, activities, tooling, resourcing, methods of stakeholder engagement, and delivery of value to the organisation.
  • Work with engineering and business stakeholders to (re)develop, improve, and integrate data pipelines and procedures for data transformation, quality control, and delivery for large-scale -omic or imaging datasets.
  • Develop tools and workflows in a cloud environment to improve automation and process efficiencies and reduce manual repetitive tasks.
  • Ensure documentation and maintenance of records of all changes to the UK Biobank resource and associated processes are recorded in a well-structured manner.
  • Contribute to the data management team's policies and procedures, leading this work when appropriate.
  • Engage with stakeholders within the Data Management team and without to define and refine the bioinformatics work backlog, ensuring work is clear, targeted, actionable, adheres to quality standards, and delivers value.
  • Engage with the research community, produce and deliver training and presentations, develop collaborations, and gather feedback to influence internal decision-making.
  • Line-manage one or more bioinformaticians, providing coaching, training, and support to ensure they have the knowledge and skills necessary to contribute to data management activities.
Requirements
  • A PhD in Bioinformatics or a related field, or equivalent experience such as 4+ years in a professional bioinformatics role.
  • Significant experience in analysis of large-scale sequencing data, including complex multistage pipeline development, reporting, and troubleshooting.
  • Excellent proficiency in programming, e.g. Python/C++/R, command line applications, and experience working on a cloud or cluster computing system.
  • Excellent problem-solving and analytical skills, and ability to prioritise workload and to work under pressure.
  • Excellent communication and stakeholder management skills, able to engage with technical and non-technical audiences.
  • Highly motivated with excellent attention to detail, able to lead and motivate members of a multi-disciplinary team.
  • Experience leading the definition and estimation of bioinformatics work, creating delivery plans, and overseeing implementation.
  • Interpersonal skills necessary for line and project management, including the ability to coach and listen, whilst providing clear expectations.
  • Proficiency with containerisation (e.g. Docker), workflow management systems (e.g. Nextflow, SnakeMake, CWL, WDL), and working with large or complex information resources, such as health records or phenotypic data.
What We Offer
  • 26 days' annual leave (which increases with length of service) plus Bank Holidays.
  • Holiday buy scheme (buy up to 1 week of additional leave per year).
  • A paid day off for your birthday (in addition to annual leave).
  • Flexible (hybrid) working, including modern offices in Stockport (relocating to new office in Manchester Science Park in 2026).
  • USS Pension Scheme which is a hybrid defined benefit/defined contribution scheme.
  • Enhanced family leave (available from day 1 of employment).
  • Cycle to work scheme.
  • Professional subscriptions reimbursement (where applicable).
  • Free gym on site.
  • On site Canteen.
  • Subsidised lunches (£5.50 contribution per day when working on site) and refreshments.
  • Free car parking.
  • Employee discounts portal.
  • 20% Discount at EE.
  • Employee Assistance Programme.
  • Eye-care scheme.
  • Annual flu vaccination.
  • Life Assurance cover.