Bioinformatics Developer

1 month ago

Hinxton, United Kingdom Embl-Ebi Full time
Job Title: Bioinformatics Developer

We are seeking a highly skilled Bioinformatics Developer to join our team at EMBL-EBI. As a key member of our team, you will be responsible for developing and maintaining tools for the functional annotation and prioritization of genomics variants, including Ensembl VEP.

Key Responsibilities:
  • Design and develop efficient methods for managing and accessing large-scale variation data for community use and to power the Ensembl websites.
  • Investigate and integrate new sources of genomic variation, phenotype association data, and prediction tools.
  • Collaborate with members of the wider Ensembl team on specific development projects and to coordinate regular data and software releases.
  • Liaise with other groups at EMBL-EBI and external collaborators to add new functionalities to our tools and agree on community standards for data representation.
  • Support our users and present our work at internal meetings and scientific conferences.
Requirements:
  • Experience in the design and development of user-friendly software or code, with proficiency in Python.
  • Experience of managing and analysing large-scale genomics data, preferably genetic variation data.
  • Experience working with large-scale relational databases, preferably MySQL.
  • Proficiency working in a UNIX/Linux environment.
  • Excellent attention to detail and the ability to deliver a high-quality product to agreed deadlines.
  • Good communication and interpersonal skills.
  • Scientific curiosity and initiative.
Desirable Skills:
  • Familiarity with the Ensembl resources, in particular Ensembl VEP.
  • Experience working in a HPC bioinformatics environment, ideally creating and managing efficient large-scale data analysis pipelines using NextFlow.
  • Experience collaborating on projects, working with colleagues from different disciplines, and using version control platforms, ideally GitHub.
  • Design and development of REST or GraphQL APIs.
  • Experience with a range of bioinformatics or statistical tools and data formats.
  • Familiarity with another programming language such as Perl and/or C.

This is an exciting opportunity to contribute to highly-used open-source bioinformatics resources and to develop domain knowledge in a fast-moving scientific area. You will work closely with a team of bioinformaticians and developers and interact with other groups at the EMBL-EBI and beyond.

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