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Scientist (Large Molecule) - Client Dedicated

2 months ago


Stevenage, Hertfordshire, United Kingdom Thermo Fisher Scientific Full time
Job Summary

We are seeking a highly skilled and experienced Scientist to join our team at Thermo Fisher Scientific. As a Biopharmaceutical Research Scientist, you will play a critical role in supporting the development of innovative drug delivery approaches and providing analytical support for the testing of various samples.

Key Responsibilities
  • Perform a variety of routine sample preparations and analysis procedures to quantitatively measure large molecule and biopharmaceutical compounds.
  • Provide analytical support for the testing of a variety of samples from GMP and non-GMP studies for Toxicology assessment, discovery, process research and development.
  • Perform work assignments accurately, with the highest quality, in a timely and safe manner.
  • Set up analytical instrumentation for analysis using appropriate methods.
  • Support the routine operation and occasional maintenance of analytical instrumentation, SOPs and regulatory procedures and guidelines.
  • Communicate analytical results to the required team and group leaders in required documentation.
  • Problem solving, either independently or with assistance, pertaining to extraction and/or instrumentation problems.
  • Provide additional data for technical, quality and compliance to protocols, methods, SOPs, client criteria and Good Manufacturing Practices (GMP) or Good Laboratory Practices (GLP).
  • Perform self and peer review of the data for accuracy and compliance with reporting requirements prior to submission to QA and issuance to customers.
Requirements
  • Bachelor Degree in Chemistry, Organic Chemistry, Chemical Engineering, Pharmaceutical Science or similar.
  • Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 2+ years) or equivalent combination of education, training, & experience.
  • Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 1-2 years).
  • 1 plus years of experience with HPLC (SEC for antibodies) in a regulated GMP lab is required.
  • Knowledge of general chemistry and separation science.
  • Experience with HPLC and Empower software.
  • Experience in Mass Spec (Glycan analysis of antibodies, Intact mass).
  • Immunoassay/bio residual experience useful (quantitative ELISA, SPR,qPCR).
  • Ability to support root cause analysis for method investigations.
  • Proficiency on technical operating systems.
  • Good written and oral communication skills.
  • Experience in analytical problem solving and troubleshooting abilities would be advantageous.
  • Time management and project management skills.
  • Ability to work in a collaborative work environment with a team.
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