Recombinant Protein Scientist

3 weeks ago

Oxford, Oxfordshire, United Kingdom CyanoCapture Full time

Position Overview

CyanoCapture, an innovative biotech firm originating from the University of Oxford, is at the forefront of bioengineering solutions for carbon capture. Our pioneering work focuses on utilizing a newly identified fast-growing photosynthetic bacterium capable of efficiently absorbing CO2 and transforming it into valuable organic compounds.

As we progress towards commercial viability alongside our technological advancements, we are in search of a dedicated Protein Biochemist. This role will involve the de novo design, characterization, and expression of high-value recombinant proteins utilizing our unique fast-growing photosynthetic strains. The ideal candidate will demonstrate exceptional discipline and multitasking abilities, coupled with a proactive mindset and sound judgment in high-pressure situations.

Key Responsibilities

  • Lead the design and execution of experiments focused on protein expression, isolation, purification, and characterization to enhance CO2 capture efficiency and biomolecule production.
  • Develop and refine advanced analytical techniques for protein quantification, including ELISA, mass spectrometry, and Western blotting.
  • Investigate structure-activity relationships (SAR) of proteins to understand their functional mechanisms.
  • Design and validate assays for the detection and functional analysis of biomolecules.
  • Collaborate with molecular biologists and bioengineers to integrate protein research into broader synthetic biology projects.
  • Analyze experimental data using advanced statistical and bioinformatics tools, presenting findings to internal teams and collaborators.
  • Contribute to scientific manuscripts, patent applications, and grant proposals, ensuring the company remains a leader in protein biochemistry.
  • Stay updated with the latest advancements in protein biochemistry and apply new methodologies to enhance research outcomes.

Qualifications

  • PhD in Biochemistry, Molecular Biology, Structural Biology, or a related field, with a strong emphasis on protein chemistry. MSc graduates with a robust background are also welcome.
  • Extensive hands-on experience in protein expression, isolation, purification, and characterization techniques.
  • Proficiency in advanced analytical methods for protein analysis, such as mass spectrometry and chromatography.
  • Strong understanding of structure-activity relationships (SAR) in proteins.
  • Experience in assay development for biomolecules.
  • Ability to work independently and collaboratively within an interdisciplinary team.
  • Strong problem-solving skills and a proven track record in designing complex experiments.
  • Excellent communication skills, with experience in publishing in peer-reviewed journals.
  • Basic lab competencies in molecular biology techniques.
  • Competent in statistics for life sciences research.
  • Basic coding experience in programming languages such as Python or R is advantageous.

Compensation and Benefits

We offer a competitive salary with incentive structures, along with 25 days of paid annual leave and additional unpaid leave options.

Travel Opportunities

There may be opportunities for short-term travel for business purposes, including presenting research at conferences or engaging in pilot projects.

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