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Postdoctoral Research Scientist in Mathematical Modelling of the Microbiome
2 months ago
We are seeking a highly skilled Postdoctoral Research Scientist to join our team at the Earlham Institute. The successful candidate will develop mathematical models of microbial communities, integrating multiple sources of data, including abundances, metabolites, and expression levels.
The role will involve the development of predictive mechanistic models, incorporating aspects of dynamical systems, such as ODEs and SDEs, as well as metabolic modelling. The candidate will also be responsible for fitting these models to data using numerical optimisation methods, such as linear programming, and Bayesian statistics and machine learning techniques, including variational inference and MCMC.
The new tools developed will be used to interpret coupled metagenome-metabolome samples from clinical samples and controlled reactor experiments, aiming to understand the role of therapeutic diets in the treatment of Crohn's disease.
The Ideal Candidate:We are looking for a candidate with a PhD in mathematics, physics, bioinformatics, or statistics, or a related subject area with a strong element of mathematical modelling. A First-class degree in any area of science is also essential. Exceptional candidates without a PhD will be considered, but a Masters degree in a quantitative subject would be essential.
The ideal candidate will have knowledge of software programming in at least one language, such as R, Python, or C/C++, and a basic understanding of calculus and statistics. Command line bioinformatics is desirable. A proven record in scientific writing and experience of oral research presentations are also essential.
Knowledge of Bayesian statistics, bioinformatics of metagenomics or metabolomics, and a biological understanding of microbial communities and metabolism would be advantageous. This position is available at an SC6 level, but candidates with sufficient experience in mathematical modelling, a demonstrated ability to organise and lead analysis of complex data sets, and potentially supervise graduate students, could be appointed to a Senior Postdoctoral Research Scientist at level SC5.
Additional Information:The salary on appointment will be within the range £35,300 to £43,750 per annum depending on qualifications and experience for the SC6 level role, and £43,550 - £54,900 per annum depending on qualifications and experience for the SC5 level criteria. This is a full-time post for a contract of three years. We encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.
