Biotechnology Specialist

4 weeks ago

Cambridge, Cambridgeshire, United Kingdom Revvity Full time
About Revvity

Rvvity is a leading life science company that delivers science-driven research solutions advancing the understanding of the genetic basis of disease and the delivery of better healthcare outcomes for patients.

Job Summary

We are seeking a highly motivated Scientist 2 to join our Core Screening Department. As a Scientist 2, you will be responsible for planning, executing, and analysing data generated from high-throughput compound screens and CRISPR-Cas9 functional genomic screens for fee-paying commercial clients.

Key Responsibilities
  • Contribute to the planning and delivery of arrayed compound screening projects, and pooled functional genomics screening projects, with appropriate supervision, where required.
  • Design, QC and analyse high throughput arrayed compound screening projects.
  • Manage compound arrayed screening activities in coordination with cell culture, compound management and automation scientists to ensure timely delivery of projects.
  • Prepare client reports and support client project tracking and communication in collaboration with the project management office.
  • Supervise more junior team members, mentoring them in techniques and troubleshooting problems.
  • Contributing to continuous improvement of screening processes and workflows to maximise effectiveness and reduce costs.
Requirements
  • Higher level degree (e.g. MSc, MRes or PhD) in Biotechnology or Biological discipline (or equivalent experience).
  • Experience of mammalian cell culture, excellent aseptic technique and performing various cell-based assays, such as those commonly employed at Revvity.
  • Experience of handling large datasets and the interpretation and communication of these data to key internal and external stakeholders.
  • Excellent interpersonal and communication skills, both written and verbal.
  • Flexibility, adaptability, and ability to work in a dynamic matrix-managed team environment and on multiple projects with constantly changing priorities and deadlines.
  • Excellent planning/organizational skills with a careful and meticulous nature.
  • Ability to perform multiple tasks simultaneously, keep accurate records, follow and give instructions, and comply with company policies.
Desirable Skills
  • Experience with transfection, transduction and techniques to modulate gene expression in mammalian cell models e.g. CRISPR-Cas9, siRNA, shRNA etc.
  • Safe handling and production of lentiviral reagents.
  • Familiarity with data visualisation software such as Prism and Tibco Spotfire.
  • Knowledge of molecular biology techniques such as DNA extraction and PCR.
  • Experience of high throughput screening and knowledge of combination screening, including analysing and interpreting compound dose response experiments.
  • Knowledge of lab information management systems (LIMS) and liquid handling robotic equipment (although full training will be provided).
  • Experience working in an Industrial / CRO setting.
About the Role

This role will be primarily lab based, with some office work required. Candidates will be expected to work on multiple tasks/projects simultaneously and should be highly self-motivated, able to work to tight timelines and be comfortable working under pressure in an environment with shifting priorities.

Note that this position requires flexible working to cover 7-day operations (rota based). The possibility of weekend work is approximately once a quarter.

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