Scientist, MSAT Specialist

2 weeks ago

London, Greater London, United Kingdom Orchard Therapeutics Full time
Job Summary

This role is pivotal in ensuring seamless communication and operational manufacturing readiness between Orchard Internal functions (MSAT, Supply Chain, GMP QA) and Orchard CDMO partner(s). The successful candidate will be a highly motivated, detail-oriented, organized MSAT scientist with relevant experience in Cell Gene Therapy products, particularly in viral vector and/or cellular therapies products.

Key Responsibilities
  • Liaison and coordination for manufacturing readiness:
    • MSAT point of contact between internal teams and CDMO to ensure manufacturing readiness
    • Facilitate planning of manufacturing documentation updates in-line with production schedule and requirements
    • Participate in weekly manufacturing internal meeting and regular meetings with CDMO
    • Coordinate timely delivery of manufacturing documentation in-line with Manufacturing schedule
    • Manage and coordinate technical review of manufacturing deviation, changes or other quality events related to manufacturing activities and ensure proper escalations and documentation resolution
    • Review manufacturing documentation and ensure alignment with current process description and control strategy
  • Process Data Analyst:
    • Support CPV efforts by ensuring accurate and timely data collection from manufacturing processes
    • Owner of the data bases design, maintenance and structural organisation
    • Actively contribute to development of manufacturing database and tools
    • Support statistical analysis on manufacturing data to identify trends, variability and opportunities for process improvement
    • Actively contribute to Trending meetings or committees
    • Generate reports and visual supports as needed
    • Maintain data integrity and ensure compliance with data management as per internal SOP and in accordance with regulations.
Requirements

Required knowledge

  • Experience in Cell and Gene Therapy in one or more of the following areas: lentiviral vectors, plasmids & cell banks, haematopoietic stem cell biology
  • Experience working with CDMO and/or third parties
  • Good knowledge of GMP
  • Good knowledge and understanding of the QbD principles

Skills & Abilities

  • Sound scientific and technical proficiency
  • Trouble-shooter, problem solver mentality
  • Excellent communicator
  • Effective collaborator able to build strong relationships with both internal and external stakeholders
  • Action oriented
  • Ability to operate in a fast-paced, multi-disciplinary industrial environment.

Education and Experience

  • At minimum, a BSc. in a relevant scientific discipline, such as Chemistry, Biochemistry, Molecular Biology, Cell Biology, Chemical Engineering, or another relevant field,
  • Relevant experience in the biotechnology or pharma industry within a MSAT, production or process development function

  • Scientist, MSAT Specialist

    3 weeks ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryThis role is pivotal in ensuring seamless communication and operational manufacturing readiness between internal functions and CDMO partners. The position will report into the head of DS/DP MSAT and will also have responsibilities with the head of Vector MSAT.Key ResponsibilitiesLiaison and coordination for manufacturing readiness:MSAT point of...

  • Scientist, MSAT Specialist

    3 weeks ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryThis role is pivotal in ensuring seamless communication and operational manufacturing readiness between internal functions and CDMO partners. The position will report into the head of DS/DP MSAT and will also have responsibilities with the head of Vector MSAT.Key ResponsibilitiesLiaison and coordination for manufacturing readiness:MSAT point of...

  • Senior Scientist, MSAT

    2 weeks ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryOrchard Therapeutics, a leading gene therapy company, is seeking a highly experienced Senior Scientist to join its Manufacturing Sciences and Analytical Technologies (MSAT) team. As a key member of the team, you will be responsible for supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP...

  • Senior Scientist, MSAT

    2 weeks ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryOrchard Therapeutics, a leading gene therapy company, is seeking a highly experienced Senior Scientist to join its Manufacturing Sciences and Analytical Technologies (MSAT) team. As a key member of the team, you will be responsible for supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP...

  • Senior Scientist, MSAT

    1 week ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryOrchard Therapeutics, a leading gene therapy company, is seeking a highly experienced Senior Scientist to join its Manufacturing Sciences and Analytical Technologies (MSAT) team. The successful candidate will be responsible for supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP manufacturing...

  • Senior Scientist, MSAT

    1 week ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryOrchard Therapeutics, a leading gene therapy company, is seeking a highly experienced Senior Scientist to join its Manufacturing Sciences and Analytical Technologies (MSAT) team. The successful candidate will be responsible for supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP manufacturing...

  • Senior Scientist, MSAT

    2 weeks ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryOrchard Therapeutics, a leading gene therapy company, is seeking a highly experienced Senior Scientist to join its Manufacturing Sciences and Analytical Technologies (MSAT) team. As a key member of the team, you will be responsible for supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP...

  • Senior Scientist, MSAT

    2 weeks ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryOrchard Therapeutics, a leading gene therapy company, is seeking a highly experienced Senior Scientist to join its Manufacturing Sciences and Analytical Technologies (MSAT) team. As a key member of the team, you will be responsible for supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP...

  • Senior Scientist, MSAT

    2 weeks ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    About the RoleWe are seeking a highly experienced Senior Scientist to join our Manufacturing Sciences and Analytical Technologies (MSAT) team at Orchard Therapeutics. As a key member of our team, you will play a critical role in supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP manufacturing...

  • Senior Scientist, MSAT

    3 weeks ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    About the RoleWe are seeking a highly experienced Senior Scientist to join our Manufacturing Sciences and Analytical Technologies (MSAT) team at Orchard Therapeutics. As a key member of our team, you will play a critical role in supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP manufacturing...

  • Senior Scientist, MSAT

    3 days ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryOrchard Therapeutics, a leading gene therapy company, is seeking a highly experienced Senior Scientist to join its Manufacturing Sciences and Analytical Technologies (MSAT) team. As a key member of the team, you will be responsible for supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP...

  • Senior Scientist, MSAT

    3 days ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryOrchard Therapeutics, a leading gene therapy company, is seeking a highly experienced Senior Scientist to join its Manufacturing Sciences and Analytical Technologies (MSAT) team. As a key member of the team, you will be responsible for supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP...

  • Senior Scientist, MSAT

    18 hours ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryOrchard Therapeutics, a leading gene therapy company, is seeking a highly experienced Senior Scientist to join its Manufacturing Sciences and Analytical Technologies (MSAT) team. As a key member of the team, you will be responsible for supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP...

  • Senior Scientist, MSAT

    22 hours ago

    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job SummaryOrchard Therapeutics, a leading gene therapy company, is seeking a highly experienced Senior Scientist to join its Manufacturing Sciences and Analytical Technologies (MSAT) team. As a key member of the team, you will be responsible for supporting the late-phase DS/DP MSAT team and process development, validation, and maintenance of all DS/DP...

  • Data Scientist

    2 weeks ago

    London, Greater London, United Kingdom Hobson Prior Full time

    MSAT Data Science SpecialistHobson Prior is seeking a highly skilled MSAT Data Science Specialist to join our team for a 12-month fixed-term contract. The ideal candidate should have a degree in Computer Science or Data Science and be proficient in Python and SQL.Key Responsibilities:Improve existing Python scripts to enhance data input into the data...

  • Data Scientist

    2 weeks ago

    London, Greater London, United Kingdom Hobson Prior Full time

    MSAT Data Science SpecialistHobson Prior is seeking a highly skilled MSAT Data Science Specialist to join our team for a 12-month fixed-term contract. The ideal candidate should have a degree in Computer Science or Data Science and be proficient in Python and SQL.Key Responsibilities:Improve existing Python scripts to enhance data input into the data...

  • Data Scientist

    1 week ago

    London, Greater London, United Kingdom Hobson Prior Full time

    MSAT Data Science SpecialistHobson Prior is seeking a highly skilled MSAT Data Science Specialist to join our team for a 12-month fixed-term contract. The ideal candidate should have a strong background in Computer Science or Data Science and be proficient in Python and SQL.Key Responsibilities:Improve existing Python scripts to enhance data input into the...

  • Data Scientist

    1 week ago

    London, Greater London, United Kingdom Hobson Prior Full time

    MSAT Data Science SpecialistHobson Prior is seeking a highly skilled MSAT Data Science Specialist to join our team for a 12-month fixed-term contract. The ideal candidate should have a strong background in Computer Science or Data Science and be proficient in Python and SQL.Key Responsibilities:Improve existing Python scripts to enhance data input into the...

  • Data Scientist

    2 weeks ago

    London, Greater London, United Kingdom Hobson Prior Full time

    MSAT Data Science SpecialistHobson Prior is seeking a highly skilled MSAT Data Science Specialist to join our team for a 12-month fixed-term contract. The ideal candidate should have a degree in Computer Science or Data Science and be proficient in Python and SQL.Key Responsibilities:Improve existing Python scripts to enhance data input into the data...

  • Data Scientist

    2 weeks ago

    London, Greater London, United Kingdom Hobson Prior Full time

    MSAT Data Science SpecialistHobson Prior is seeking a highly skilled MSAT Data Science Specialist to join our team for a 12-month fixed-term contract. The ideal candidate should have a degree in Computer Science or Data Science and be proficient in Python and SQL.Key Responsibilities:Improve existing Python scripts to enhance data input into the data...