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Senior Research Associate

2 months ago


Cambridge, Cambridgeshire, United Kingdom EC Resourcing Full time
Job Description

**Job Summary**

EC Resourcing is seeking a highly skilled Senior Research Associate to join our client's growing Biology team in a biopharmaceutical company based near Cambridge. The successful candidate will be responsible for interrogating the efficacy and safety of our client's cell therapy in a range of sophisticated in vitro assays and in vivo models.

Key Responsibilities

  • Plan and execute a wide range of robust experiments, technical studies, and tasks, working independently based on protocols and in line with departmental objectives.
  • Differentiate iPSC/HSC cells and characterize via flow cytometry, western blot, ELISA, and immunofluorescence.
  • Cultivate cell lines and primary cells utilized in therapeutic programs for lead selection and profiling.
  • Liaise with programme leaders and matrix team members for data exchange and cell culture/assay planning, as well as generation and characterization of reporter cell lines.
  • Timely, accurate recording and analysis of results and compliance with data integrity procedures.
  • Timely presentation of data to the department and wider company.
  • Contribute to critical interpretation of data to draw results-driven hypotheses, with influence on project/function direction.
  • Work to existing SOPs and risk assessments and contribute to generating new ones as appropriate.
  • Adopt software, instruments, automation, and ways of working which help further improve data robustness & data meta-analysis.

Requirements

  • A relevant BSc, MSc or equivalent experience in the areas of cell culture (immune cells, iPSC, HSC, ESC).
  • Experience with flow cytometry.
  • Experience with developing assays for detection of cytokine or antibodies.
  • Experience with ELISA and/or western blot.
  • Proven lab-based experience with protocol design, data recording, processing, and storage.
  • Fluency in spoken and written English.
  • Scientific drive, technical ability, autonomy & confidence, backed by solid topical knowledge and project experience.
  • Proficiency with critical interpretation of data and implementation into an experimental cascade.
  • Communication in a clear, well-structured, and professional manner with key stakeholders within the company on a regular basis.
  • Contribution to authoring of technical and science reports which will feed into IND filings.
  • Awareness of latest scientific literature in company-relevant projects and general scientific areas.