Bioinformatician

**Job Purpose**
We have an exciting opportunity for a bioinformatician to work on single cell transcriptomics in the School of Infection and Immunity, University of Glasgow. You will join a team of bioinformaticians and bench biologists, in the research group of Professor Matt Berriman. The group investigates the development of schistosome parasites and creates reference data resources for the broader research community. The post is available either for an experienced bioinformatician (grade 7) or a less experienced bioinformatician (grade 6) that wants to further develop their skills.
The post-holder will take the lead on an exciting project to elucidate fundamental processes in parasite development. Schistosomes are blood flukes that cause diseases in many low
- and middle-income countries. These deadly pathogens have complex life cycles involving human hosts and water borne vectors. Basic research is needed to discover vulnerabilities that can be exploited in the search for future interventions to control parasites.
You will analyse single-cell sequencing data to uncover new biology from schistosomes as they develop from juveniles to adults, working closely with lab-based colleagues to iteratively validate findings. You will also collaborate with other bioinformaticians to integrate findings across the life cycle, helping to create a reference temporal cell atlas of development as a community resource for schistosome research.

**Main Duties and Responsibilities**
1. Plan and conduct research individually and jointly in accordance with project deliverables and research strategy of the team.
2. Contribute and perform internationally competitive analyses and interpretation of experimental datasets.
3. Document research output including analysis and interpretation of all data, maintaining records and databases, drafting technical/progress reports and papers as appropriate.
4. Keep up to date with current knowledge and recent advances in the field/discipline
6. Communicate progress and plans effectively, through regular project-planning meetings
7. Contribute to problem-solving discussions within the team and provide input to strategic decisions to help move the team forward.
8. Present work at international and national conferences, at internal and external seminars and workshops to enhance your research profile and that of the team
9. Assist in the development of proposals to secure funding from internal and external bodies to support future research.
10. Develop and maintain collaborations with colleagues across the School and wider research community.
11. Pro-actively contribute to team/group meetings/seminars/workshops and School research group activities to enhance the wider knowledge, outputs and culture of the School.
12. Organise, supervise, mentor and train undergraduate and/or postgraduate students and less experienced members of the project team to ensure their effective development.
13. Contribute to teaching activities (eg demonstrating etc) and associated administration in consultation with the Line Manager.
14. Engage in personal, professional and career development, to enhance both specialist and transferable skills in accordance with desired career trajectory.
15. Contribute to the enhancement of the University’s international profile in line with the University’s Strategic Plan “World Changers Together”

**For appointment at grade 7**:

16. Perform the above duties with a higher degree of independence and responsibility, taking a leading role in discussions and project-planning.
17. Troubleshoot problems independently without regular mentorship.
- Initiate and guide problem solving discussions.

**Qualifications**

**Essential**:
Or
Ability to demonstrate the competencies required to undertake the duties associated with this level of post having acquired the necessary knowledge and skills in a similar role.

**For appointment at Grade 7**:
Or
Ability to demonstrate the competencies required to undertake the duties associated with this level of post having acquired the necessary knowledge and skills in a similar role.

**Knowledge and Skills**

**Essential**:

C1 Intermediate level scripting in Python
C2 Good knowledge of R
C3 Proficiency in Unix/Linux
C4 Up to date knowledge of bioinformatics and functional genomics, particularly sequencing based approaches.
C5 Excellent interpersonal and presentation skills
C6 Excellent time management skills
C7 Ability to prioritise, manage workload, and deliver agreed activities consistently
C8 Research creativity and cross-discipline collaborative ability.
C9 Excellent interpersonal skills including team working and a collegiate approach.
C10 Excellent communication skills (oral and written), including the ability to communicate complex concepts clearly and concisely.
C11 Attention to detail

**For appointment at Grade 7**:

C12 In-depth knowledge of R
C13 Up to date knowledge of single-cell RNA sequencing and analysis approaches
C14 Ability to