Associate Principal/principal Scientist

3 weeks ago

Nottingham, United Kingdom Sygnature Discovery Limited Full time

Looking to advance your career in in vitro DMPK? _

**Why work for us?**:

- You will work from **modern, state-of-the-art laboratories** and **solve challenging problems for our clients.**:

- Our **global clients **range from big pharma and biotechs to academic and charitable organisations.
- **Teamwork and communication** are as important as the science we do - how we interact and communicate with our clients is part of our success.
- We foster a culture of **collective responsibility and communal working**. If you’re challenged by a problem, your project team, department and the company will support you to find a solution.
- We want you to have **a long and rewarding career** at Sygnature. We can offer a **challenging, stimulating and fulfilling** role in a sociable team that’s **passionate about drug discovery.** It’s an extremely motivating and humbling experience to discover a lifesaving drug.

**The opportunity**:

- You’ll work as part of Sygnature’s integrated drug discovery teams on projects with Chemistry, bioscience, computational chemistry, and _in-vivo_ colleagues as the DMPK project representative.
- You will take a leading role in troubleshooting issues as they arise, be responsible and accountable for assay validations and automation and the assessment of new methodologies and technologies.
- You will take an active role in the recruitment and retention of key talent to maintain a high-performing team.
- You will offer support to business development activities in order to grow the business.

**Key requirements**:

- You will hold a B.Sc. with M.Sc. (and preferably a Ph.D.) in Pharmaceutical Sciences, Chemistry, Biochemistry or a related discipline.
- You will possess a thorough knowledge of absorption, distribution, drug metabolism and pharmacokinetics obtained within the pharmaceutical industry together with an excellent working knowledge of the drug discovery process.
- You will be able to demonstrate leadership and project management skills.
- You will have excellent written and verbal communication skills.
- For a Principal Scientist, a minimum of 7-10 years of biotech and/or pharmaceutical industry experience in discovery DMPK is essential.

In return you will receive an excellent training and benefits package, including a highly competitive salary which is reviewed annually, a bonus scheme, a well-regarded pension scheme, and private medical insurance. All our benefits are tailored to enhancing your experience at Sygnature as it is important to us that you share in our success.

We also recognise that the environment you work in is a priority, so we have built a collaborative and supportive culture with plenty of opportunities to grow and succeed, tailored to individual and business needs. This includes an excellent set of bespoke training and development courses to accelerate both your scientific and personal career growth.

Since 2011, 34 compounds discovered by Sygnature for customers have entered pre-clinical development. So far, 17 of these have progressed to clinical trials (Phases I, II and III). In 2017, Sygnature Discovery received the prestigious Queen’s Award for Enterprise for International Trade, in 2020 the Medilink Outstanding Achievement Award, and in 2021 the Bionow Company of the Year Award.

1) Your CV

2) A covering letter that briefly outlines your suitability for the role and your current notice period (if applicable)

3) Confirmation of your status of eligibility to work in the UK (we can consider sponsoring potential employees with relevant levels of qualifications and experience under a Skilled Worker Visa).

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