Molecular Biologist

**Molecular Biologist**

**Medical Research Council - Mary Lyon Centre**

**Harwell Campus, Oxfordshire**

**Fixed Term until 31 March 2027**

**£32,005 per annum**

**About Us**
The Mary Lyon Centre at MRC Harwell (MLC) is located on the Harwell Campus, a thriving science hub specialising in technologies in the fields of health, space and energy. We focus on preclinical research using mouse models, which supports clinical researchand therapy discovery. The MRC is an excellent place to develop yourself further and a range of training & development opportunities will be available to you, including professional registration with the Science Council.

**About the Role**

The Mary Lyon Centre (MLC) at the Medical Research Council Harwell Institute requires a skilled molecular biologist to reinforce a busy service that provides support to the UK research community with mouse genome engineering, expression studies and analysisof genetically altered mouse embryos.

The MCB group at the MLC undertakes generation and quality control of a broad range of targeted alleles as a bespoke service for individual laboratories. The group requires a research specialist in Molecular Biology to provide capacity to evolve and implementcomplex genome engineering production and validation processes. The post-holder will also provide support for both the design and the analysis of mouse genetic alterations. The post-holder will be based in the Molecular and Cellular Biology group and willcoordinate some genome engineering projects and functional analysis studies in in vitro models and/or mouse adult and embryonic tissues. They will work in a twelve-strong team under the guidance of the Molecular and Cellular Biology Deputy Manager

**About you**
- PhD in Biomedical Sciences (plant or microbiology specialists need not apply), or MSc with a strong track record of relevant molecular biology work
- Previous work with genetically modified animal materials
- Previous experience in genotyping of genetically edited materials
- Design and implementation of gene targeting and/or genome editing strategies
- Previous experience with Sanger sequencing DNA sequence analysis software
- Experience of delivery of scientific projects
- Experience of basic molecular biology techniques, including PCR, qPCR, Southern or western blotting
- Experience of methods employed for mouse genome engineering

**Benefits**:
Choosing to come to work at the MRC (part of UK Research and Innovation (UKRI)) means that you will have access to a whole host of benefits, from a defined-benefit pension scheme and excellent holiday entitlement, to access to employee shopping/travel discountsand a salary sacrifice cycle-to-work scheme. In addition, you will have the opportunity to contribute to the work of a world-class medical research organisation.

The MRC values the diverse skills and experience of its employees and is committed to achieving equality of treatment for all. Our objectives are that all individuals shall have equal opportunities for employment and advancement on the basis of their skills,aptitudes and abilities.

**How to Apply