Research Assistant/associate

3 weeks ago

Newcastle upon Tyne, United Kingdom Newcastle University Full time

**Salary**:
Research Assistant - £31,396 to £32,982 per annum
Research Associate - £33,966 per annum

Newcastle University is a great place to work, with excellent benefits. We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.

**Closing Date**: 13 June 2024

The Role

We are looking for an experienced researcher to work on projects aimed at characterizing tissue and circulating biomarkers in genetic muscle diseases.

In these projects we are going to use a variety of new technologies to study muscle biopsies of patients with facioscapulohumeral muscular dystrophy (FSHD) and other muscle disorders, and to detect circulating biomarkers in patients’ plasma and serum. The final aim is to identify the key molecular pathways that are dysregulated in FSHD and other myopathies and to confirm them in vitro in cellular models of the disease. You will work in the John Walton Muscular Dystrophy Research Centre, a centre for translational research in genetic neuromuscular diseases with around 90 team members.

As part of our commitment to career development for research staff, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

This post is full time, fixed term until 31 September 2026

The post will be based at the John Walton Muscular Dystrophy Research Centre (JWMDRC) at Newcastle University.

Key Accountabilities
- Although working under the general guidance of an academic or Principal Investigator, they should contribute with new ideas, including enhancements to the technical or methodological aspects of their studies, thus providing substantial ‘added value’
- Determine appropriate methodologies for research, with advice and support where required
- Assess research findings for the need/scope for further investigations
- Contribute to the writing up of their research and its dissemination, either through seminar and conference presentations or through publications
- Present research findings, either at conferences or through publications in reputable outlets appropriate to the discipline
- Involvement in the supervision, with guidance, of final year undergraduate research projects and in providing support to postgraduate research students or Research Assistants
- Start to develop an awareness of University structures, policies and procedures and relevant issues in the higher education, research, social and political environment
- Write, with appropriate support, proposals for individual research funding or, where funders do not permit this, contribute to the writing of collective bids
- May contribute to events celebrating the public engagement of science/social sciences/humanities
- Will need to work with the support staff and, on occasions, with undergraduate and postgraduate students, and interact intellectually with other academic members of the Institute

The Person

Knowledge, Skills and Experience
- Experience in working with human tissue samples
- Experience in cell culture, especially of muscle-derived cells such as myoblasts and mesenchymal progenitors
- Experience in analysis of protein expression in muscle samples using immunofluorescence or western blot
- Knowledge of and experience with molecular biology techniques, especially with RNA analysis and quantification
- Experience with flow cytometry and with the preparation of samples for sorting

Desirable
- Previous experience with transcriptomics studies
- Previous experience with proteomics studies
- Experience with writing research publications and grants

Attributes and Behaviour
- Advanced skills directly related to the research projects
- High level of analytical and problem-solving capability
- Ability to communicate complex information with clarity and to encourage the commitment of others
- Good time management and ability to prioritise to meet deadlines

**Qualifications**:

- A PhD and experience in the research area required (Research Associate Level)

Newcastle University is a global University where everyone is treated with dignity and respect. As a University of Sanctuary, we aim to provide a welcoming place of safety for all, offering opportunities to people fleeing violence and persecution.

At Newcastle University we hold a silver Athena Swan award in recognition of our good employment practices for the advancement of gender equality. We also hold a Race Equality Charter Bronze award in recognition of our work towards tackling race inequality in higher education REC. We are a Disability Confident employer and will offer an interview to disabled applicants who meet the essential criteria for the role as part of the offer and interview scheme.

In addition, we are a member of the Euraxess initiative supp

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