System Modelling and Simulations Expert

2 weeks ago

London, United Kingdom GSK Full time

**Site Name**: UK - Hertfordshire - Ware RD, UK - Hertfordshire - Stevenage, UK - Hertfordshire - Ware, UK - London

**Posted Date**: Feb 9 2024

We are looking for a Systems Modelling & Simulations Expert to join our team in the UK.

As experts in the field our team implements Process Systems Engineering, Modelling and Simulations approaches on medicines in development to increase understanding and greatly reduce labor, materials and time required to identify commercial manufacturing processes. The team provides support to the entire GSK portfolio across on Small Molecules Drug Substances and Drug Products, Biopharmaceuticals and Vaccines.

The Systems Modelling & Simulation Experts also support upskilling project team members to expand the use of models and simulations, as well as work with internal and external technical experts to develop and maintain core simulation software platforms. We also champion the integration of new ways of working into existing pharmaceutical “Quality by Design” workflows (eg; Process Design, Control Strategy Identification, Risk Assessment), regulatory filing strategies, and product life-cycle support.

**Key Responsibilities (include)**:

- Develop and deploy Process Systems Engineering, Modelling and Simulations approaches to the diverse GSK portfolio across small Molecules Drug Substance, Drug Product, Biopharmaceuticals and Vaccines.
- Pioneer and develop novel approaches including but not limited to mechanistic modelling, systems modelling, multiscale modelling (e.g. Computational Fluido Dynamics).
- Translate mathematical models to computer models using software platforms (e.g. gPROMS, DynoChem, Ansys, COMSOL) or by developing custom solutions (e.g. in Matlab, Python, etc.)
- Use engineering, chemical, biological or materials science knowledge to postulate mechanisms for physiochemical and biological processes and develop or modify existing mathematical models to describe those mechanisms.
- Direct experimentation and the analysis required to develop models and assess their credibility (e.g. parameter estimation).
- Stay current with new modeling techniques through external publications and conferences and academic and pre-competitive collaborations.
- Leverage external expertise and funding through alliances and academic collaborations to identify, develop and internalize novel modelling approaches for process development.
- As part of a matrix process development team, use Process Systems Engineering, Modeling and Simulations to efficiently deliver team priorities, including but not limited to Process Design, quantitative Risk Assessment, Identification of Critical Process Parameters / Design Space and implementation of advanced process controls.
- Provide and coordinate training and real-time support to expand the use of modeling (simulations) across the Development and Manufacturing environments.
- Work closely with the Subject Matter Experts in Pharmaceutical Quality by Design, regulatory and Information Technology to integrate process modelling into process development routine ways of working and drive cultural changes in the adoption of Digital, Data and Analytics across the organization.
- Advocate and comply with Good Manufacturing Practice (GMP) and Data Integrity requirements for recording experiments and associated data and authoring technical reports including scientific peer review and data checking.
- Provide input to budgets, recommend capital purchases of software supporting modeling.
- Comply with requirements on Safety, Quality for the Patient and GSK policies and procedures (sites and department).

**Location**: We are flexible (to some extent) on location. Successful applicants can work from our Ware, Stevenage or Head-Office (London) locations.

**About You**:
We are open-minded about your level of experience (we encourage recent graduates as well as more experienced applicants to apply), but we are seeking people who are passionate about simulation and modelling solutions.

**Basic Qualifications**:

- Vocational / higher level qualification in a relevant discipline (eg; MSc, PhD, etc) with an emphasis on development and implementation of process models and simulations.
- Ability to translate mathematical models into computer programs (eg; using Matlab, Python, gPROMS or similar software tools).

**Preferred Qualifications**:

- Experience with engineering software (eg; gPROMS, Dynochem, Ansys, COMSOL) and with programming languages (eg; Python, Matlab).

**Benefits**:
GSK offers a range of benefits to its employees, which include, but are not limited to:

- Competitive base Salary
- Annual bonus based on company performance
- Opportunities to partake in on-the-job training courses
- Opportunities for support for professional development and chartership (accreditations and professional bodies)
- Access to healthcare and wellbeing programmes
- Employee recognition programmes

If you would like to learn more about our company wide benefits and

  • Modelling and Simulation Engineer

    3 days ago

    London, United Kingdom SkyBridge U.K. Ltd Full time

    Our project has been operating discretely since 2017, since then we have been working towards our goal of changing the world of logistics and mobility via future technology Aerospace vehicle solutions. We are currently in search of Modelling and Simulation Engineer. Your role will consist of researching, developing and maintaining the dynamic models of our...

  • Chemical Process Engineer

    4 weeks ago

    London, United Kingdom ICM Group Full time

    Location: Saudi Arabia (Must be willing to relocate and work in Saudi) Minimum Requirements: Must have a bachelor's degree in chemical engineering. Must have a minimum of 10 years of experience with Process Simulation and Modeling technologies. Must demonstrate expertise in process engineering end flowsheet-based processes simulation. Must possess...

  • Chemical Process Engineer

    6 days ago

    London, United Kingdom ICM Group Full time

    Location: Saudi Arabia (Must be willing to relocate and work in Saudi) Not sure what skills you will need for this opportunity Simply read the full description below to get a complete picture of candidate requirements.Minimum requirements:Must have a bachelor's degree in chemical engineering.Must have a minimum of 10 years of experience with Process...

  • Chemical Process Engineer

    1 day ago

    London, United Kingdom ICM Group Full time

    Job Description Location: Saudi Arabia (Must be willing to relocate and work in Saudi) Minimum requirements: Must have a bachelor's degree in chemical engineering. Must have a minimum of 10 years of experience with Process Simulation and Modeling technologies. Must demonstrate expertise in process engineering end flowsheet-based processes...

  • Chemical Process Engineer

    1 month ago

    London, United Kingdom ICM Group Full time

    Location: Saudi Arabia (Must be willing to relocate and work in Saudi) Minimum requirements: Must have a bachelor's degree in chemical engineering. Must have a minimum of 10 years of experience with Process Simulation and Modeling technologies. Must demonstrate expertise in process engineering end flowsheet-based processes simulation. Must possess...

  • Chemical Process Engineer

    7 days ago

    London, United Kingdom ICM Group Full time

    Job DescriptionLocation: Saudi Arabia (Must be willing to relocate and work in Saudi) Minimum requirements:Must have a bachelor's degree in chemical engineering.Must have a minimum of 10 years of experience with Process Simulation and Modeling technologies.Must demonstrate expertise in process engineering end flowsheet-based processes simulation.Must possess...

  • Chemical Process Engineer

    1 month ago

    London, United Kingdom ICM Group Full time

    Location: Saudi Arabia (Must be willing to relocate and work in Saudi) Minimum requirements: Must have a bachelor's degree in chemical engineering. Must have a minimum of 10 years of experience with Process Simulation and Modeling technologies. Must demonstrate expertise in process engineering end flowsheet-based processes simulation. Must possess...

  • Chemical Process Engineer

    1 month ago

    London, United Kingdom ICM Group Full time

    Location: Saudi Arabia (Must be willing to relocate and work in Saudi) Minimum requirements:Must have a bachelor's degree in chemical engineering.Must have a minimum of 10 years of experience with Process Simulation and Modeling technologies.Must demonstrate expertise in process engineering end flowsheet-based processes simulation.Must possess a...

  • Chemical Process Engineer

    2 hours ago

    London, United Kingdom ICM Group Full time

    Location: Saudi Arabia (Must be willing to relocate and work in Saudi) Not sure what skills you will need for this opportunity Simply read the full description below to get a complete picture of candidate requirements.Minimum requirements:Must have a bachelor's degree in chemical engineering.Must have a minimum of 10 years of experience with Process...

  • Chemical Process Engineer

    4 weeks ago

    London Area, United Kingdom ICM Group Full time

    Location: Saudi Arabia (Must be willing to relocate and work in Saudi) Minimum requirements:Must have a bachelor's degree in chemical engineering.Must have a minimum of 10 years of experience with Process Simulation and Modeling technologies.Must demonstrate expertise in process engineering end flowsheet-based processes simulation.Must possess a...

  • Software Engineer

    4 weeks ago

    London, United Kingdom Northrop Grumman Full time

    Requisition ID: R10103457 Your Opportunity to Define Possible. Our Opportunity to Deliver the Nation’s Security. Together. Role Clearance Type: You must be able to gain and maintain the relevant UK Government clearance in the line with the job role (SC) Location: Remote / Customer Site (Fareham/Gosport) About Your Opportunity: A rare...

  • Simulation Software Engineer

    1 month ago

    London, United Kingdom Wayve Technologies Ltd Full time

    Who are we? Our team is the first in the world to use autonomous vehicles on public roads using end-to-end deep learning. With our multi-national world-class technical team, we’re building things differently. We don’t think it’s scalable to tell an algorithm how to drive through hand-coded rules and expensive HD maps. Instead, we believe that machine...

  • LP Engineer

    1 month ago

    London, United Kingdom ICM Group Full time

    Work Location: Saudi (must be willing to relocate) Overview The Global Optimizer Development Department’s (GOD) charter is to optimize crude allocation and the operations of global manufacturing facilities in order to maximize revenue, increase profitability, and capture international market opportunities. The division also acts as the LP gatekeeper for...

  • LP Engineer

    1 month ago

    London, United Kingdom ICM Group Full time

    Work Location: Saudi (must be willing to relocate) OverviewThe Global Optimizer Development Department’s (GOD) charter is to optimize crude allocation and the operations of global manufacturing facilities in order to maximize revenue, increase profitability, and capture international market opportunities. The division also acts as the LP gatekeeper for...

  • LP Engineer

    6 days ago

    London, United Kingdom ICM Group Full time

    Work Location: Saudi (must be willing to relocate) A high number of candidates may make applications for this position, so make sure to send your CV and application through as soon as possible.OverviewThe Global Optimizer Development Department’s (GOD) charter is to optimize crude allocation and the operations of global manufacturing facilities in order to...

  • LP Engineer

    4 weeks ago

    London, United Kingdom ICM Group Full time

    Work Location: Saudi (must be willing to relocate) A high number of candidates may make applications for this position, so make sure to send your CV and application through as soon as possible.OverviewThe Global Optimizer Development Department’s (GOD) charter is to optimize crude allocation and the operations of global manufacturing facilities in order to...

  • LP Engineer

    7 days ago

    London, United Kingdom ICM Group Full time

    Job DescriptionWork Location: Saudi (must be willing to relocate) OverviewThe Global Optimizer Development Department’s (GOD) charter is to optimize crude allocation and the operations of global manufacturing facilities in order to maximize revenue, increase profitability, and capture international market opportunities. The division also acts as the LP...

  • LP Engineer

    1 day ago

    London, United Kingdom ICM Group Full time

    Job Description Work Location: Saudi (must be willing to relocate) Overview The Global Optimizer Development Department’s (GOD) charter is to optimize crude allocation and the operations of global manufacturing facilities in order to maximize revenue, increase profitability, and capture international market opportunities. The division also acts as the...

  • LP Engineer

    4 weeks ago

    London Area, United Kingdom ICM Group Full time

    Work Location: Saudi (must be willing to relocate) OverviewThe Global Optimizer Development Department’s (GOD) charter is to optimize crude allocation and the operations of global manufacturing facilities in order to maximize revenue, increase profitability, and capture international market opportunities. The division also acts as the LP gatekeeper for...

  • Simulator Design Engineer

    1 month ago

    London, United Kingdom Holtec International Full time

    Holtec International and its subsidiary companies are designing an unfailingly safe and secure source of clean energy using nuclear fission, called the SMR-160 small modular reactor. The position is offered by SMR LLC as a member of the Holtec International family, a global turnkey supplier of equipment and systems for nuclear, solar, geothermal, and fossil...