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Research Assistant
5 months ago
In particular, the work will seek to evaluate the zoonotic potential of certain wildlife coronaviruses and will also seek to identify the specific molecular factors that govern their cross-species transmission. This will involve a range of experimental techniques, including genome-scale CRISPR knockout and other host factor screening approaches, virus pseudotyping and the use of reverse genetics for evaluation of virus tropism, along with other experimental and computational approaches. Ultimately, the project aims to utilise these findings to develop new frameworks that can more broadly evaluate virus zoonotic potential, in order to better identify viruses with epidemic or pandemic potential.
Recent publications involving our approaches and related projects include: Rihn et al., PLOS Biology 2021 (PMID: 33630831); Wickenhagen et al., Science 2021 (PMID: 34581622); Sugrue et al., PLOS Pathogens 2022 (PMID: 36399512); Shaw, et al., PLOS Biology 2021 (PMID: 34491982); Rihn et al., J Virol 2019 (PMID: 31375575).
Applicants will be expected to work collaboratively with colleagues and contribute to a positive, friendly and dynamic research environment. Although the Research Assistant will predominantly help support the research of the team, they will also be encouraged to bring their own initiative and contributions to the project.
Fixed-term: The funds for this post are available for 2 years in the first instance.
The interview date for the role is: To be confirmed
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.