Mass Spectrometry Research Officer

7 months ago

Edinburgh, United Kingdom University of Edinburgh Full time

**Grade UOE6 - £31,396 - £36,024**

**Edinburgh Cancer Research Centre within the IGC**

**Full-Time 35 Hours Per Week**

**Contract Type - Fixed-Term 3 years
We are looking for a Mass Spectrometry Research Officer to join the Edinburgh Cancer Research team.

The post-holder will assist in the operation of the mass spectrometry laboratory from experimental proteomic, lipidomic and metabolomic sample preparation through to data analysis. To support the operation of the IGC mass spectrometry facility (IGC-MS) across the IGC, University of Edinburgh and beyond. The post-holder will be trained to operate and maintain a Q Exactive, Q Exactive+ and Fusion Lumos, timsTOF SCP mass spectrometer and associated on-line and off-line HPLC systems. As well as operating Robotic Workstations (2 Kingfisher, Tecan 780, cellenONE). The post-holder will use this instrumentation to prepare and analyse samples for proteomic and metabolomic analysis using a wide variety of preparative techniques. Proteomic sample preparation techniques will include urea extraction, immunoprecipitation (& co-immunoprecipitation), off-line HPLC, FFPE protein extraction and single-cell processing. The post-holder will maintain accurate records of various parameters of instrument performance for experimental quality control. To record details of all samples and all consumables usage for audit purposes and to keep consumables well stocked. Will perform data analyses in a variety of different software packages, including Proteome/Compound Discoverer, Mascot, MaxQuant, Spectronaut, Xcalibur, Skyline, XCMS, mzMine, LipiDex and LipiBlast. To present the data to researchers in a clear format and to revisit and further mine data where required. And will keep up to date with chromatography and mass spectrometry techniques through reading, attending meetings and liaising with vendors as well undertake method development to improve the level of support for research in the IGC.

This post is advertised as full-time (35 hours per week), however, we are open to considering part-time or flexible working patterns. We are also open to considering requests for hybrid working (on a non-contractual basis) that combines a mix of remote and regular on-campus working

**The Opportunity**:
The position offers the opportunity to collaborate groups form across the world and to be trained on cutting-edge instrumentation.

**Your skills and attributes for success**:

- Appropriate degree, with some post-graduate research experience.
- Some knowledge of mass spectrometry.
- Some knowledge of liquid chromatography
- Collaborative
- Organised
- Ability to communicate with customers
- Working knowledge of basic bioinformatics

**Click to view a copy of the full **job description **here**

**As a valued member of our team you can expect**:
An exciting, positive, creative, challenging and rewarding place to work. We give you support, nurture your talent and reward success. You will benefit from a competitive reward package and a wide range of staff benefits, which includes a generous holiday entitlement, a defined benefits **pension scheme **, **staff discounts, **family friendly initiatives **, flexible working and much more. Access our **staff benefits page **for further information and use our **reward calculator **to find out the total value of pay and benefits provided.

The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.

Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our **right to work webpages **(opens new browser tab)

Interviews will be held **in due course.

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