Medical Technical Officer

2 weeks ago

London, United Kingdom Synnovis Full time

The Synnovis Cancer Genetics laboratory at Guy’s Hospital is part of the South East Genomics Laboratory Hub (SEGLH) and is the designated provider of adult solid tumour testing for the whole of the SEGLH geography. Large scale expansion and transformation of the service is underway to ensure equity of access to the NHSE National Genomic Test Directory for Cancer.

We are seeking to recruit a Medical Technical Officer (MTO1) at AfC band 4 equivalent who will participate in the technical work and general housekeeping duties for all areas of the service. Training and rotational opportunities are available within the cancer genetics team and these will be determined by individual competency and laboratory requirements in order to support the provision of a flexible and efficient service.

The successful applicant will demonstrate an enthusiasm for learning and have excellent written and verbal communication skills in order to work effectively with staff at all levels within the Cancer Genetics team and other sections of the genomic laboratory hub.

This is a great opportunity to join a rapidly growing service, utilising the latest technologies within a large fully integrated genomic laboratory hub with more than 120 staff.

You will contribute to the clinical work of the Cancer Genetics team in line with your own skills and competencies, undertaking a broad range of technical laboratory activities. Specific duties will depend on the area in which you are working but will include preparation of reagents and solutions, DNA and RNA extractions from a variety of human tissue types and processing samples ready for genetic analysis using a variety of techniques including real time quantitative PCR for measurable residual disease (MRD) monitoring in acute myeloid leukaemia (AML) and a variety of cytogenetic processes. All MTO1 staff participate in general housekeeping duties such as reagent management, emptying bins, maintaining a clean and tidy laboratory environment and unpacking deliveries.

Previous practical experience of working in a diagnostic genetic laboratory would be helpful, however appropriate training will be given in order to meet the required levels of competency. This is an entry level post which would be suitable for new life science and biomedical science graduates who are keen to work in the field of diagnostic cancer genetics. There are excellent opportunities available for career development.

The Cancer Genetics team is comprised of around 50 administrative, scientific and technical staff within the cytogenetic and molecular genetic laboratories. Testing is provided for patients with a wide range of adult solid tumours and haematological malignancies, in order to provide diagnostic and prognostic information and inform treatment decisions. The service includes a substantial nationally and internationally renowned acute myeloid leukaemia (AML) mínimal residual disease (MRD) monitoring service which has close links with the King’s College NIHR clinical trials AML MRD unit. The laboratory is accredited according to UKAS 15189 standards and is an accredited training laboratory for the provision of the cancer genetic Scientific Training Programme (STP) and the Molecular Pathology of Acquired Disease Higher Specialist Training (HSST) programme.

You will have a suite of learning opportunities available through The Synnovis Way Development programme, the Scientific Learning and Development Fund and the Synnovis Academy through which you can receive funding / support for advanced qualifications.

At Synnovis, we are currently shaping the future of pathology services by creating a world-leading Hub and Spoke pathology network with our NHS partners. A large part of this modernisation will involve moving 70% of our services to a purpose built, state of the art Hub laboratory in the heart of London.

**Responsibilities**:
The post holder will work across the cytogenetic and molecular genetic teams within Cancer Genetics as required - expectations will be tailored to individual experience and competencies.

Technical duties
- Use laboratory information systems according to protocols
- Undertake routine and complex sample preparation using accuracy and precision to correctly employ the procedures and protocols applicable to cancer genetics, including handling of patient information. Laboratory duties include, but are not restricted to; manual and/or robotic DNA and RNA extractions from a variety of human tissue types, preparing samples for molecular analysis using techniques such as RT-PCR and Next Generation Squencing (NGS), setting up and processing slides for FISH analysis
- Undertake an appropriate proportion of the total workload of the Cancer Genetics section and take responsibility for accuracy of the work undertaken
- Undertake accurate and precise data entry on the laboratory computer system under supervision of more senior staff
- Provide cover for staff at the same or lower grade depending on

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