Research Officer

**Research Officer (Gene Regulation and Genomics)**:

- Employer- Walter and Eliza Hall Institute- Location- Melbourne (Suburb), Greater Melbourne (Inner) (AU)- Salary-
- Closing date- 1 Mar 2024- Discipline
Life Science
Job Type
Postdoctoral, Researcher
Employment - Hours
Full time
Duration
Fixed term
Qualification
PhD
Sector
Charity/NGO- You need to sign in or create an account to a job.

An excellent opportunity is available for a **Research Officer (Gene Regulation and Genomics)** in the Epigenetics and Development Division at Australia’s pre-eminent biomedical research institute.

**About the position**
There is an exciting opportunity for a talented and motivated researcher with expertise in gene regulation or human immunology to join the laboratory of Dr Hamish King in the Epigenetics and Development Division at the Walter and Eliza Hall Institute.

The King lab studies how defects in the epigenetic control of gene expression are involved in human disease, with a particular interest in B cells and the immune system. The lab is building upon recent single-cell transcriptomic and epigenomic profiling of the human immune system (King et al. 2021a Science Immunology eabe6291, King et al. 2021b Science Immunology eabh3768) which identified transcription factors, chromatin-associated proteins and gene regulatory elements involved in dynamic immune cell states and diverse immune diseases. To investigate these gene regulatory mechanisms, we take an interdisciplinary approach and leverage biochemistry, functional and single-cell genomics, immunology, and bioinformatics to make fundamental discoveries about gene regulation in health and disease.

**Selection Criteria**
Applicants should possess a PhD (or be near completion of a PhD) in molecular biology, gene regulation and/or genomics, and have a strong track record and understanding of mechanisms of gene regulation, such as enhancer biology, transcription factors, chromatin-modifying complexes, and/or epigenetic modifications.

This role requires experimental expertise in functional genomics assays (e.g. ATAC-seq, RNA-seq, ChIP-seq) and/or CRISPR/Cas9 (epi)genomic editing strategies. Experience with viral transductions, flow cytometry and bioinformatics are highly desired, but not essential. This position will suit an enthusiastic and motivated individual with an independent work ethic, proven project management experience and a collaborative mindset. Excellent communication and interpersonal skills are also required, including the ability to write for publication and presentation of research at conferences.

**Terms of appointment**

General enquiries are encouraged and can be directed to Hamish King.

**Application closing date: 1 March 2024.