Clinical Research Fellow- Haematology

4 weeks ago

Manchester, United Kingdom The Christie NHS Foundation Trust Full time

The Haematology and TYA services are seeking to appoint to a senior/junior Haematology Clinical Trials Research Fellow post to work alongside the research team and existing roles within the Palatine treatment centre. In 2014 the Palatine treatment centre opened as a purpose-built facility for the Haematology and Transplant Unit and Teenage and Young Adult (TYA) services.

Many clinical and scientific staff members have contributed to research, education and clinical developments, making The Christie proud to be responsible for having ‘world firsts’ and playing a crucial role in the advancement of cancer treatments and care for over 100 years.

The stem cell transplant program at the Christie was established in 1982 since when it has undertaken almost 3000 procedures. The department currently performs 120-160 transplants per year. In 2018, the Christie was selected as one of 7 first wave UK centres for delivery of CAR-T therapy. The unit is fully accredited for treatment with JACIE and the first patients are being treated in 2019.

The Christie is one of Europe’s leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country.

We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years.

We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.

DUTIES AND RESPONSIBILITIES

Clinical Trials

The position is suitable for individuals who wish to gain further experience in experimental medicine & Phase I trials, including first-in-human trials.

A diverse range of clinical research trials are in progress & following training, the post holder will participate in these studies as a co-/sub-investigator. These include Phase I trials of small molecule inhibitors, combination / multi-modality Phase I trials, and trials of CAR-T and bispecific antibodies. The post holder will be involved in managing all aspects of trial patients (both in outpatient & in-patients setting), across all areas of haematological malignancy, through new patient consultation, consent & screening patients & reviewing patients at follow-up appointments

The post holder will attend Safety Review Committee meetings (usually remotely) to discuss trial patients. This will involve close liaison with Principal Investigators, referring consultant body across the north of England and Wales & other team members. The appointee will interface with external stakeholders such as CROs & pharmaceutical sponsors.

The appointee will undertake the administrative duties associated with the care of their patients. The appointee will be encouraged to be involved in the development & planning of new studies.

The Fellow will maintain a level of continuing professional development. There is the potential to present research work & the post holder will be expected to be involved in writing papers & reviews. The post holder will also be required to undergo an annual appraisal.

The Fellow will be expected to contribute to both undergraduate & postgraduate teaching, and aspects of clinical governance & audit.

Inpatient and day unit

The Haematology Fellow will join the existing Palatine ward Haematology clinical team ensuring that

all patients across the department have optimal daily clinical cover. Working as part of the existing ward team which includes 2 Haematology ST doctors, 1 TYA Oncology Senior clinical fellow, 1 Junior Oncology fellow and 3 x ward-based IMTs who cover the 31 bedded-ward.. The haematology fellow will have a particular responsibility for supervision of patients on the new 4 inpatient bedded unit due to open early 2021 and the adjacent ambulatory care unit. The Haematology service is supported by an attending consultant, with 2 scheduled consultant ward rounds per week and daily consultant level input as required.

Outpatients

There will be an opportunity to attend the Haematology departmental weekly teaching sessions and to participate in Haematology outpatient clinics focusing on patients enrolled in clinical trials.

Person requirements

Flexible working and cross-cover with existing Palatine Ward middle grade haematology roles (Haematology Specialist Registrars and the Trust Grade post) will be a requirement within this post.

The post holder will require good communication skills in order to work effectively/collaboratively within the broader teams, but also in order to engage and build

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