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Associate Scientist

4 months ago


Alderley Edge, United Kingdom Medicines Discovery Catapult Full time

Based at Alderley Park, Medicines Discovery Catapult is a national facility connecting the UK community to accelerate innovative drug discovery. We provide unique scientific capabilities and act as a gateway to UK resources and expertise, supporting UK SMEs to drive the development and industrialisation of new approaches for the discovery of new medicines.

By validating new ways of discovering medicines and driving key talent and expertise across the sector, we will support the UK life sciences industry, SMEs and innovators to deliver growth for the UK economy and maintain the UK’s heritage position as a global leader in medicines R&D. Ultimately, new industrialised technologies are vital for delivering new medicines to patients, faster.

**The Role**:
There is now an opportunity for an Associate Scientist to join the Mass Spectrometry (MS) team, which has been established at MDC, Alderley Park. This individual will work closely with our MS scientists, providing essential technical support to enable delivery of a portfolio of partnered projects. This fully lab-based individual will be responsible for the maintenance of a range of MS technologies and associated sample preparation devices and they will support projects through deployment of established protocols and workflows, ensuring compliance with laboratory standards, including GCLP.

This opportunity to join a world class laboratory team in this high-profile national organisation, while collaborating with SMEs, Biotechs and leading academic institutes and researchers, should provide a fantastic platform for career development.

**Main duties and responsibilities**
- Provision of lab support to the MS team, working with established protocols and methods to enable effective delivery of the project portfolio
- Calibration and basic maintenance of mass spectrometry instrumentation.
- Calibration, maintenance, and basic troubleshooting of HPLC systems.
- Maintenance and calibration, where required, of automated sample preparation devices used in MS and Mass Spectrometry Imaging (MSI) workflows (e.g. Matrix coating and acoustic dispensing devices).
- Liaison with engineers for equipment and instrumentation maintenance and technical troubleshooting.
- Implementation of effective lab processes, experimental records, and safety.
- Preparation of MS laboratory standards and solutions.
- Preparation of tissue samples for MS imaging.
- Use of automated sample preparation devices.

**Qualifications and experience**
- Experienced in essential laboratory skills (e.g. pipetting, aseptic techniques), following experimental protocols and adherence to safe working practices.
- Experienced in calibration and basic use of mass spectrometry instrumentation.
- Excellent communication and teamwork skills
- Knowledge of working under GCLP guidelines would be beneficial.
- Experienced in preparation of laboratory standards and solutions.
- Excellent time management and organisation skills, including record keeping.
- Excellent attention to detail

**Closing date: Friday 20th January 2023