Bioinformatician, Oxford-gsk Institute of Molecular

2 weeks ago


Oxford, United Kingdom University of Oxford Full time

The newly established Oxford-GSK Institute of Molecular & Computational Medicine (IMCM), operating within the Nuffield Department of Medicine, is seeking to appoint a Bioinformatician to join the multi-disciplinary, science driven team delivering bioinformatics excellence to understand the patterns and mechanisms in neurodegenerative disease.

You will be responsible for conducting processing and detailed analysis of a variety of ‘omics datasets, including bulk and single cell transcriptomic data, whole-genome and exome DNA sequencing data, proteomic data and metabolomic data across a range of parallel projects. You will provide bioinformatics advice to the IMCM research project teams and plan new analyses that will progress the IMCM research projects. Keeping meticulous, detailed records of your work and committing to performing cloud-based analyses on the IMCM data platform is a key part of this role, along with preparing manuscripts for publication and contributing to written and oral presentations/reports as required.

It is essential that you hold a relevant post-graduate qualification in bioinformatics, computational biology, biostatistics, applied mathematics, or related discipline, and have experience handling and analysing various types of ‘omics data types, such as RNA-Seq, whole genome or exome sequencing data, single cell profiling, ChIP-Seq, proteomics, and metabolomics. You will be able to plan and oversee programmes of technical work to a successful conclusion by agreed deadlines. Experience of programming languages including Python and R is essential, along with experience of developing and maintaining bioinformatics pipelines and workflows. Previous experience of working on neuroscience projects, such as on Parkinson’s disease, Alzheimer’s disease, ALS or another neurodegenerative disease is highly desirable.

This position is offered full time on a fixed term contract until 30 September 2027 and is funded by GSK.

Interviews are to be held on 23 May 2024.



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