Research Associate
3 days ago
We are currently looking for a Research Associate to join a Start-up Cancer Biology Biotechnology company based in the Cambridgeshire area. As the Research Associate you will be responsible for independent research developing first-in-class Cancer Therapeutics.You will be responsible for researching combination drugs to develop new cancer treatments.
You will conduct a range of cellular and molecular assays to assess proof-of-concept and target validation from their novel products, including developing in vitro CRISPR/Cas9 and high through-put screens.
KEY DUTIES AND RESPONSIBILITIES:
Your duties as the Research Associate will be varied however the key duties and responsibilities are as follows:
1. Maintain human cell-lines through mammalian Cell Culture and differentiation techniques.
2. Support routine plasmid cloning, bacterial transformation and plasmid extraction as well as other routine molecular Biology techniques including but not limited to DNA, RNA and Protein extraction, PCR and RT-qPCR.
3. Support proof-of-concept and target validation activities by independently designing and execution of biological plans.
4. Record all data and analyse results for presentation.
ROLE REQUIREMENTS:
1. Relevant degree in a Life Sciences discipline ideally focused on Molecular and Cellular Biology. Mammalian cell culturing is required.
2. Experience with a range of Molecular Techniques including but not limited to, Vector transfection, DNA / RNA / Protein extraction, DNA Electrophoresis, PCR, RT-qPCR and cloning and bacterial transformation.
3. A working knowledge and understanding of genome-edited cells using techniques not limited to Immunohistochemistry, Fluorescent microscopy and flow-cytometry.
Key Words: Molecular Biology | Cell Culture | Mammalian Cells | Cloning | DNA | RNA | Vector | Transfection | Transformation | PCR | RT-qPCR
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