Associate Principal Scientist

1 month ago

Cheshire, United Kingdom SRG Full time

**Job Title: Associate Principal Scientist -Formulation and Scale up**

**Type: Permanent**

**Salary: Highly attractive**

**Location: North West, England**

SRG is currently working exclusively with a highly successful, rapidly expanding contract development and manufacturing organisation focused on providing expert intelligence and support to their partners, driven by their capabilities.

As a result of expansion, we are looking for an expert formulator to drive the formulation science and associated regulatory components of client projects and prove mentoring and coaching to more junior formulation staff. We are looking for someone who isup to date with the latest technical advances in formulation science and, where appropriate, identify opportunities for introducing those technologies into the business.

**The key responsibilities of the role are to**:

- Bring formulation and process expertise to design and guide the development for a range of simple and complex drug products to support early and late clinical phases
- Bring the right / specific scientific thinking together with pragmatic design thinking to deliver product and technology solutions for client's compounds and products
- Demonstrate comprehensive knowledge of material properties and characterisation of physical attributes of dosage forms
- Provide expertise in drug delivery and material characterisation to contribute to the development activities for challenging compounds and delivery vehicles (e.g. poorly solubles, new modalities, targeted systems)
- Work closely with the analytical scientists to ensure appropriate testing of formulations is carried out
- Understand and articulate global regulatory requirements for a CMC submission and design the product strategy accordingly
- Act as pharmaceutical development project leader / manager for some client projects
- Contribute to continuous improvement of formulation capability, including keeping abreast of state-of-the-art formulation techniques.
- Provide direction, oversight and coaching of other members of staff

**Essential Requirements**:

- Educated to PhD and 3+ years' experience in Pharmaceutical Sciences or related field, or Bachelor's degree 6+ years' experience in formulation development in the pharmaceutical industry
- Expertise in oral and parenteral formulation development and optimisation
- Experience of progressing the formulation components of various drug projects through different development phases (discovery to launch) across global markets
- Wide ranging experience of interactions with global regulatory authorities
- Good understanding of ICH quality guidelines and global CMC regulatory requirements
- Experience with drug-delivery systems such as modified-release formulations, nano-particulate systems or liposomal formulations
- Proven ability to coach and mentor others
- Valid UK driving license

**SRG are the UK number 1 recruitment company specialising in the science, engineering, clinical, pharmaceutical, food/FMCG, renewable, biotech, chemicals and medical devices sectors.**

Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.

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