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2 weeks ago
**Project: Hox genes and the diversification of neural networks**
Applications are invited from highly motivated individuals who are interested in fundamental mechanisms of neuronal development. The Postdoctoral Research Fellow position is available to work with Dr. Jimena Berni and her group at the Brighton and Sussex Medical School, University of Sussex. The position is fully funded by the BBSRC for three years, to start in April 2023 or as soon as possible thereafter.
Our research objective is to radically push forward our understanding on the mechanism of circuit diversification. We use _Drosophila_ as a model system and investigate how Hox genes orchestrate the diversification of motor circuits during nervous system development.
We approach this question at three levels:
1) Circuit: To define the fundamental differences subserving the specialization of circuits.
2) Function: To show how divergent connectivity patterns modify neuronal function.
3) Genetic: To analyse the role of Hox genes in the specification of circuit assembly and function.
- genetics, CRISPR/cas9, behavioural experiments) as well as working with collaborators: Electron microscopy neuronal reconstructions with Prof. Albert Cardona (Univ. of Cambridge and MRC-LMB), and electrophysiology experiments with Prof. Richard Baines (Univ. of Manchester).
The Berni lab is part of Sussex Neuroscience, a highly collaborative and interdisciplinary community of over 50 neuroscience researchers that organises a wide range of scientific and career development activities.
- The University of Sussex values the diversity of its staff and students and we welcome applicants from all backgrounds._
- You can find out more about our values and our EDI Strategy, _Inclusive Sussex_, on our webpages._
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