Postdoctoral Fellow

**Postdoctoral Fellow**:

- Employer- Massachusetts General Hospital/Division of Infectious Diseases- Location- Boston, Massachusetts- Salary- Salary dependent on level of experience + benefits- Closing date- 5 Apr 2024- Discipline
Life Science
Job Type
Postdoctoral
Employment - Hours
Full time
Duration
Permanent
Qualification
PhD
Sector
Academia- You need to sign in or create an account to a job.

The overall focus of the Charles lab is to decrease the global burden of mucosal and enteric infections of import affecting resource-poor and marginalized populations. More specifically, work in the lab is focused on furthering our understanding of host-pathogen and immune responses during human infection by _V. cholerae _(the cause of cholera) and _Salmonella enterica_ serovar Typhi and Paratyphi A (the primary cause of enteric fever) and to identify immunogenic antigens or molecular signatures for vaccine and diagnostic assay development. Research in the lab utilizes human patient samples and tumor cell lines to perform a variety of immunological, functional, and genome-scale assays to address 1) fundamental questions about protective immunity during human infection with _S._ Typhi or _V. cholerae_ and the novel mechanisms these pathogens utilize to cause infection and 2) to develop rapid diagnostic and seroepidemiological tools that can be used in resource-limited settings. Methods applied in the lab include, but are not limited to, ELISAs, multiplex bead-based assays, flow cytometry, and RNA-seq.