Senior Scientist

4 weeks ago

Cambridge, United Kingdom CK Group- Science, Clinical and Technical Full time

CK Group are working in partnership with Nxera Pharma UK Limited (formerly Sosei Heptares) to recruit a lab-based Senior Scientist in Protein Binder Discovery based in Granta Park, Cambridge.

Company:
Nxera Pharma is a technology powered biopharma company, in pursuit of new specialty medicines to improve the lives of patients with unmet needs in Japan and globally, focused on therapeutic areas in inflammation diseases, neurology and immunology. 
 
The Role:
The successful candidate will join the Protein Binders Discovery Team at Nxera Pharma and will also be part of the wider Biochemistry and Biophysics teams. The successful candidate will use phage display expertise to select protein binders against therapeutic membrane protein targets to enable structure determination and drug discovery efforts. 

The role will include the following responsibilities:

Screening phage display libraries against membrane protein targets 
Protein engineering of VHH frameworks
Subcloning of plasmid constructs for expression 
Biophysical evaluation of VHH hits
Your Background:

PhD (or MSc with equivalent lab experience) in a relevant area of biology
Theoretical and practical expertise in phage display technologies and selection techniques 
Experience working with phage antibody libraries and preferably VHH display
Strong and evidenced molecular biology proficiency 
Experience of screening techniques (eg ELISA, cell binding assays etc)
Experience of affinity maturation
Analytical thinking and good problem-solving skillsDESIRABLE:

Experience of measuring affinity using either BLI or SPR
Experience of library build (either affinity maturation or immunised, naïve or synthetic libraries)
Experience in working with membrane proteins (in particular GPCRs)
Computational expertise focussed around protein binder design would be advantageous 
Apply:
It is essential that applicants hold entitlement to work in the UK. Please quote job reference 99230 in all correspondence

  • Senior Scientist

    4 weeks ago

    Cambridge, United Kingdom Reed Scientific Full time

    Reed Scientific are proud to be partnering with a growing biotech startup in the Cambridge area. We are currently recruiting for a scientist position with them, details as follows: Role: Senior Protein Scientist Contract: Permanent Hours: Full-time, Monday - Friday **Salary**: Competitive Essential Qualifications: PhD or equivalent experience in...

  • Senior Scientist

    4 weeks ago

    Cambridge, United Kingdom CY Partners Full time

    **Senior Scientist - Biopharmaceutical Characterisation** **Cambridgeshire Based** **£30,000 - £45,000 + Excellent Benefits** Do you have substantial experience in Biological and Biophysical Characterisation of Biopharmaceuticals? Would you like to work for a leading pharmaceutical organisation in the Cambridge area? My client is an established and...

  • Senior Computational Scientist

    3 weeks ago

    Cambridge, United Kingdom SRG Full time

    I am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist. Are you a senior Computational...

  • Senior Computational Scientist

    3 weeks ago

    Cambridge, United Kingdom SRG Full time

    I am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist.Are you a senior Computational...

  • Senior Computational Scientist

    3 weeks ago

    Cambridge, United Kingdom SRG Full time

    I am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist.Are you a senior Computational...

  • Senior Computational Scientist

    3 weeks ago

    Cambridge, United Kingdom SRG Full time

    I am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist.Are you a senior Computational...

  • Senior Computational Scientist

    3 weeks ago

    Cambridge, United Kingdom SRG Full time

    I am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist.Are you a senior Computational...

  • Senior Computational Scientist

    6 days ago

    Cambridge, United Kingdom SRG Full time

    Job DescriptionI am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist.Are you a senior...

  • Senior Scientist

    1 week ago

    cambridge, United Kingdom JR United Kingdom Remote Work Freelance Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits.Who we areWe are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior Production Scientist

    3 days ago

    Cambridge, United Kingdom CK GROUP Full time

    CK Group are recruiting for a Senior Production Scientist on behalf of a growing Cell Therapy CDMO to be based at their site in Cambridge on a permanent basis. **About the Company**: Our client is based in state of the art facilities for multi-product GMP manufacturing, they are currently undergoing an extensive period of growth and development, and are...

  • Senior Research Scientist

    1 week ago

    Cambridge, United Kingdom CK GROUP Full time

    CK Group are recruiting for a Senior Research Scientist to join a company in the Pharmaceutical industry working initially on a contract basis for 12 months. **Hourly Rate**: £25.00 PAYE or £32.00ph UMB **Essential Requirements**: - Formal training and proven expertise (PhD + postdoc, or equivalent experience) in biochemistry, in-vitro pharmacology or a...

  • Senior Scientist

    1 week ago

    Cambridge, Cambridgeshire, United Kingdom JR United Kingdom Full time

    We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits.Who we areWe are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier talent.The client...

  • Senior Research Scientist

    5 days ago

    Cambridge, United Kingdom Hays Specialist Recruitment Limited Full time

    This is an exciting opportunity to join the Mechanistic and Structural Biology department in Cambridge as a laboratory-based Senior Research Scientist. As a Senior Research Scientist, you'll be part of the Mechanistic and Structural Biology Department -a team where they collaborate to support projects aiming to impact patients' lives. The team is responsible...

  • Senior Scientist

    4 weeks ago

    Cambridge, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits.Who we areWe are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior Scientist

    4 weeks ago

    Cambridge, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits.Who we areWe are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior Scientist

    3 weeks ago

    Cambridge, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits. Who we are We are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior Scientist

    4 weeks ago

    Cambridge, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits.Who we areWe are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior Scientist

    4 weeks ago

    Cambridge, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits.Who we areWe are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior/Laboratory Research Scientist

    1 week ago

    Cambridge, Cambridgeshire, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, Onsite Senior Scientist Research & Development The Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics. Academic/Major: ~ PhD in Molecular or Cellular Biology, Biomedicine, Immunology or...

  • Senior/Laboratory Research Scientist

    1 week ago

    Cambridge, Cambridgeshire, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, Onsite Senior Scientist Research & Development The Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics. Academic/Major: ~ PhD in Molecular or Cellular Biology, Biomedicine, Immunology or...