Head of Biostatistics

1 month ago

England, United Kingdom Warman O'Brien Full time

Head of Biostatistics - United Kingdom - Hybrid / Remote - Excellent Remuneration & Benefits
I am working exclusively for a SME biotech who are looking for a Director of Biostatistics (Senior also considered) to join as a senior member of a cross-functional asset team, reporting to the Chief Development Officer (CDO). You will also be responsible for developing trial designs that address study objectives that will support regulatory approval, including contributing to Clinical Development Plans, submissions, and post-submission strategies, preparations, and defences. You will provide guidance and management to CRO based statisticians and data scientists to ensure high quality and timely deliverables, whilst managing resources, setting priorities, and ensuring consistency and adherence to standards therein.


Provide statistical support for clinical studies, including study design, sample size calculations, patient randomization, statistical analyses, interpretation of data, and reporting of results.
Present and defend complex statistical solutions to all levels of the company’s governance, key stakeholders and external regulatory bodies in a clear, concise, complete, and transparent manner that provide influence on key decisions.
Review/Develop the Statistical Analysis Plan, including the definition of derived data sets, and the design of statistical tables, figures, and data listings for clinical summary reports.
Plan and conduct statistical analysis (ISS, ISE), post-hoc analyses, exploratory analyses, or analyses requested by regulatory agencies.
Collaborate in writing regulatory document, reviews sections of regulatory submissions, attends meetings with regulatory agencies to support drug registration.
Promote, investigate, develop, and implement novel statistical approaches/methodologies, for relevant statistical issues (in collaboration with academic groups, as needed).
Where appropriate, provide guidance and management to statisticians to ensure high quality and timely deliverables.
As required, perform ad hoc and exploratory data analyses.
Where appropriate, provide training, seminars and/or coaching in statistical topics to non-statistical company staff.


You’ll have an entrepreneurial mindset and the ability to bring creative solutions to challenges. PhD or MSc in statistics or biostatistics or related scientific field with clinical trials, drug development, pharmaceutical industry or healthcare experience. Proficiency in scientific computing/programming (SAS, R or Python) and implementation of advanced statistical analysis, data manipulation, graphing & simulation.
Excellent interpersonal, communication, writing and organizational skills.
Demonstratable expertise in applying knowledge of general and cutting edge statistical / clinical trials methodology to solve complex statistical problems in the clinical development area and ensure alignment with regulatory agencies and industry standards.
Experience in preparing and participating in global regulatory agency interactions.
Significant experience on a full development asset providing statistical guidance and input to the clinical development plan, regulatory Health Authority submissions (NDA/BLA/MAA) and defence and acted as the lead statistician on responding to submission-related questions from Health Authorities.

  • Deputy Head

    2 weeks ago

    England, United Kingdom Independent Association of Prep Schools Full time

    This is an exciting opportunity for a Deputy Head teacher. We are seeking to appoint an inspirational and enthusiastic Deputy Head to join the Senior Leadership Team at Upton House School. Detail The successful candidate will work closely with the Head to make a significant contribution to the school’s strategic development, and to the smooth day-to-day...

  • Head of Netball

    1 week ago

    England, United Kingdom Independent Association of Prep Schools Full time

    We are looking to appoint an inspiring and dedicated Head of Netball, to cover a period of Maternity and to lead and develop the Netball programme across both the Prep and Senior School. The Head of Netball is a visible and active role within the College community, providing motivational leadership to the Netball programme and contributing to the vision...

  • Head of Netball

    2 weeks ago

    England, United Kingdom Independent Association of Prep Schools Full time

    Are you passionate about netball and shaping young athletes into champions? We are looking to appoint an inspiring and dedicated Head of Netball, to cover a period of Maternity and to lead and develop the Netball programme. Detail Are you passionate about netball and shaping young athletes into champions? We are looking to appoint an inspiring and...

  • Head of Netball

    2 weeks ago

    England, United Kingdom Independent Association of Prep Schools Full time

    Are you passionate about netball and shaping young athletes into champions? We are looking to appoint an inspiring and dedicated Head of Netball, to cover a period of Maternity and to lead and develop the Netball programme. Detail Are you passionate about netball and shaping young athletes into champions? We are looking to appoint an inspiring and...

  • Head of Netball

    4 days ago

    England, United Kingdom Independent Association of Prep Schools Full time

    Are you passionate about netball and shaping young athletes into champions? We are looking to appoint an inspiring and dedicated Head of Netball, to cover a period of Maternity and to lead and develop the Netball programme. Detail Are you passionate about netball and shaping young athletes into champions? We are looking to appoint an inspiring and...

  • Head of Netball

    1 week ago

    England, United Kingdom Independent Association of Prep Schools Full time

    Are you passionate about netball and shaping young athletes into champions? We are looking to appoint an inspiring and dedicated Head of Netball, to cover a period of Maternity and to lead and develop the Netball programme. Detail Are you passionate about netball and shaping young athletes into champions? We are looking to appoint an inspiring and...

  • Head of Netball

    1 week ago

    England, United Kingdom Independent Association of Prep Schools Full time

    Are you passionate about netball and shaping young athletes into champions? We are looking to appoint an inspiring and dedicated Head of Netball, to cover a period of Maternity and to lead and develop the Netball programme. Detail Are you passionate about netball and shaping young athletes into champions? We are looking to appoint an inspiring and...

  • Head of Policy, Research and Development

    2 weeks ago

    England, United Kingdom University of Sussex Full time €54,395 - €64,914

    Hours : Full-time hours considered up to 1FTE. Requests for flexible working options will be considered (subject to business need). Applications must be received by midnight of the closing date. An exciting opportunity exists to join the University of Sussex in a new leadership role as Head of Research Development and Initiatives. This role will...

  • Head of Policy, Research and Development

    2 weeks ago

    England, United Kingdom University of Sussex Full time €54,395 - €64,914

    Hours : Full-time hours considered up to 1FTE. Requests for flexible working options will be considered (subject to business need). Applications must be received by midnight of the closing date. An exciting opportunity exists to join the University of Sussex in a new leadership role as Head of Research Development and Initiatives. This role will...

  • Head of Policy, Research and Development

    1 week ago

    England, United Kingdom University of Sussex Full time €54,395 - €64,914

    Hours : Full-time hours considered up to 1FTE. Requests for flexible working options will be considered (subject to business need). Applications must be received by midnight of the closing date. An exciting opportunity exists to join the University of Sussex in a new leadership role as Head of Research Development and Initiatives. This role will...

  • Head of Policy, Research and Development

    1 week ago

    England, United Kingdom University of Sussex Full time €54,395 - €64,914

    Hours : Full-time hours considered up to 1FTE. Requests for flexible working options will be considered (subject to business need). Applications must be received by midnight of the closing date. An exciting opportunity exists to join the University of Sussex in a new leadership role as Head of Research Development and Initiatives. This role will...

  • Head of Research Development and Initiatives

    2 weeks ago

    England, United Kingdom University of Sussex Full time €54,395 - €64,914

    Hours : Full-time hours considered up to 1FTE. Requests for flexible working options will be considered (subject to business need). Closing Date : 26 June 2026. Applications must be received by midnight of the closing date. Expected Interview Date: Week of 15 th July 2024 Expected Start Date : September 2024  An exciting opportunity exists to join...

  • Head of Research Development and Initiatives

    2 weeks ago

    England, United Kingdom University of Sussex Full time €54,395 - €64,914

    Hours : Full-time hours considered up to 1FTE. Requests for flexible working options will be considered (subject to business need). Closing Date : 26 June 2026. Applications must be received by midnight of the closing date. Expected Interview Date: Week of 15 th July 2024 Expected Start Date : September 2024  An exciting opportunity exists to join...

  • Head of Research Development and Initiatives

    1 week ago

    England, United Kingdom University of Sussex Full time €54,395 - €64,914

    Hours : Full-time hours considered up to 1FTE. Requests for flexible working options will be considered (subject to business need). Closing Date : 26 June 2026. Applications must be received by midnight of the closing date. Expected Interview Date: Week of 15 th July 2024 Expected Start Date : September 2024  An exciting opportunity exists to join...

  • Head of Research Development and Initiatives

    1 week ago

    England, United Kingdom University of Sussex Full time €54,395 - €64,914

    Hours : Full-time hours considered up to 1FTE. Requests for flexible working options will be considered (subject to business need). Closing Date : 26 June 2026. Applications must be received by midnight of the closing date. Expected Interview Date: Week of 15 th July 2024 Expected Start Date : September 2024  An exciting opportunity exists to join...

  • Head of Research Development and Initiatives

    1 week ago

    England, United Kingdom University of Sussex Full time

    Hours : Full-time hours considered up to 1FTE. Requests for flexible working options will be considered (subject to business need). Closing Date : 26 June 2026. Applications must be received by midnight of the closing date. Expected Interview Date: Week of 15 th July 2024 Expected Start Date : September 2024  An exciting opportunity exists...

  • Head of School

    1 month ago

    England, United Kingdom University of Plymouth Full time

    At the University of Plymouth, innovation is at the core of our ethos. We're not just about teaching and research; Excellence is our standard, being one of the few universities awarded triple gold for teaching excellence in the recent Teaching Excellence Framework. Join Us and Lead the Plymouth Business School: The Head of School is an opportunity to...

  • Head of School

    3 weeks ago

    England, United Kingdom University of Plymouth Full time

    At the University of Plymouth, innovation is at the core of our ethos. We're not just about teaching and research; Excellence is our standard, being one of the few universities awarded triple gold for teaching excellence in the recent Teaching Excellence Framework. Join Us and Lead the Plymouth Business School: The Head of School is an opportunity to...

  • Head of School

    1 month ago

    England, United Kingdom University of Plymouth Full time

    At the University of Plymouth, innovation is at the core of our ethos. We're not just about teaching and research; we're committed to exploring new horizons and making a meaningful impact. Excellence is our standard, being one of the few universities awarded triple gold for teaching excellence in the recent Teaching Excellence Framework. Join Us...

  • Head of School

    3 weeks ago

    England, United Kingdom University of Plymouth Full time

    At the University of Plymouth, innovation is at the core of our ethos. We're not just about teaching and research; we're committed to exploring new horizons and making a meaningful impact. Excellence is our standard, being one of the few universities awarded triple gold for teaching excellence in the recent Teaching Excellence Framework. Join Us...