Drug Discovery Chemist

2 weeks ago


United Kingdom invoX Pharma Limited Full time

Drug Discovery Chemist - Antibody Drug Conjugates

Department: Protein Sciences

Employment Type: Permanent - Full Time

Location: invoX Cambridge

Reporting To: Christel Veyssier

Description

invoX is a research-driven global biopharmaceutical company using next-generation technology platforms to discover and develop innovative medicines that can change the lives of people around the world. Our vision is to be a leading global biopharmaceutical company with an advancing pipeline of products addressing the unmet healthcare needs of patients.

To help continue our growth and success, we are looking for a Drug Discovery Chemist - Antibody Drug Conjugates , to join our Protein Sciences team. You will be a highly self-motivated, independent, and creative Principal Scientist, with a background in synthetic chemistry and you’ll have significant experience in antibody drug conjugates / drug discovery and development. This is an exciting opportunity to play a key role in the development of innovative antibody drug conjugates from design, synthesis, characterisation to candidate selection. As invoX continues to grow, this is a compelling opportunity to work in a fast-paced business.

invoX is a wholly owned subsidiary of Sino Biopharmaceutical Limited, a Hong Kong listed global top 40 pharmaceutical company with more than 24,000 employees.

Key Responsibilities
  • Designing and evaluating linker-drug payload constructs and bioconjugation methodologies to achieve the desired target product profiles.
  • Developing in vitro and in vivo methods to assess stability, efficacy, pharmacokinetic and safety profiles of drug candidates in line with project goals.
  • Overseeing and coordinating day-to-day research activities in collaboration with CRO partners to ensure the timely delivery of technical objectives.
  • Reviewing in vitro and in vivo data to monitor progress and inform technical strategy and decision-making
  • Drafting and reviewing research documentation, such as reports, presentations, publications, manuscripts, patent applications, and/or summaries. Dissemination of research findings to internal and external audiences through publication and presentation of research results. Translation of validated research data and processes into publications or patent applications.
  • Maintaining a high level of familiarity with relevant scientific and technical literature with the ability to appropriately apply new developments to internal research projects.
Skills, Knowledge & Expertise

You will be skilled in the interpretation of in vitro and in vivo data to inform technical strategy and decision making and will be expected to function with a high degree of independence whilst working collaboratively within a multidisciplinary team, across organisations.

  • PhD or equivalent in a Chemistry-related subject
  • Relevant research experience, ideally involving significant time in an industry setting
  • Expertise in synthetic chemistry with an emphasis on bioconjugation, ideally in the field of antibody drug conjugates
  • Experience of the drug discovery process, ideally in the development of antibody drug conjugates
  • Able to work successfully and confidently in collaboration with CROs, the management team, advisors, and consultants
  • Excellent communication (both verbal and written) and interpersonal skills
  • Ability to effectively present results, interpret in vitro and in vivo data, and draw conclusions regarding presented material
  • Able to understand drug discovery project goals and methods and think critically and creatively to generate ideas to positively impact project goals
Why work for invoX?

We get things done, we keep things simple and we are driven by the science. We are ambitious so we work hard to create an environment where we can take smart risks. We want to be innovative so encourage debate and collaboration to challenge the usual way of doing things. We love our celebrations and socialising, which make invoX a fun and diverse place to work. And most of all, everyone has the opportunity to make a difference.

For this position candidates must be eligible to live and work in the UK

#J-18808-Ljbffr

  • United Kingdom Manufacturing Chemist Full time

    Sygnature Discovery has appointed Louisa Jordison as CFO. Jordison joined Sygnature Discovery in 2019 as Director of Strategic Planning, and enters the company’s boardroom following more than a decade in Deloitte’s corporate finance advisory team and a position as Senior Strategic Planning Manager at Experian. She will replace Victoria Tabiner, who is...

  • Analytical Chemist

    3 weeks ago


    United Kingdom Kindeva Drug Delivery Company Full time

    Posted Monday, January 8, 2024 at 5:00 AM Kindeva is a leading global contract developer and manufacturer (CDMO) with delivery platform expertise in Autoinjector, Inhalation, Transdermal/Intradermal Patch Technologies. We partner with our customers to improve patient outcomes around the world. Together, as One Team, we will manufacture many more tomorrows....


  • United Kingdom BenevolentAI Group Full time

    We are looking for a highly experienced Senior Principal Cheminformatics Data Scientist, with a keen interest in small molecule drug design, to join our Cheminformatics & Computational Chemistry team. The Cheminformatics & Computational Chemistry team is a high performing cross-functional team that seeks to apply their knowledge to a diverse range of...


  • United Kingdom BenevolentAI Group Full time

    We are looking for a highly experienced Lead Cheminformatics Data Scientist, who specialises in AI/ML with a keen interest in small molecule drug design, to lead our Cheminformatics team within our Cheminformatics & Computational Chemistry team. The Cheminformatics & Computational Chemistry team is a high performing cross-functional team that seeks to...


  • United Kingdom CDM Recruitment Ltd - Life Sciences Full time

    Type: Full-time £CDM Life Science are recruiting on behalf of a leading innovator in the field of life sciences, dedicated to advancing scientific research and improving human health. As an Analytical Chemist, you will play a crucial role in supporting research and development efforts by providing analytical expertise and conducting chemical analyses. The...

  • Specialist Analytical Chemist

    Found in: Jooble UK C2 - 2 weeks ago


    United Kingdom CDM Recruitment Ltd - Life Sciences Full time

    Type: Full-time £CDM Life Science are recruiting on behalf of a leading innovator in the field of life sciences, dedicated to advancing scientific research and improving human health. As an Analytical Chemist, you will play a crucial role in supporting research and development efforts by providing analytical expertise and conducting chemical analyses. The...


  • United Kingdom invoX Pharma Limited Full time

    Department: Protein Sciences Employment Type: Permanent - Full Time invoX is a research-driven global biopharmaceutical company using next-generation technology platforms to discover and develop innovative medicines that can change the lives of people around the world. Our vision is to be a leading global biopharmaceutical company with an advancing...


  • United Kingdom Kindeva Drug Delivery Company Full time

    Kindeva is a leading global contract developer and manufacturer (CDMO) with delivery platform expertise in Autoinjector, Inhalation, Transdermal/Intradermal Patch Technologies. The Kindeva Drug Delivery Ltd. site in Loughborough manufactures and packages pharmaceutical and medical products in various forms. This role will be working as part of a team...


  • United Kingdom Metrion Biosciences Ltd. Full time

    Research Associate Scientist/Scientist I Metrion Biosciences (‘Metrion’) is a UK-based, ion channel focused Contract Research Organisation (CRO) providing high-quality in vitro preclinical drug discovery and safety profiling services. customer base who access our comprehensive suite of drug discovery services; medicinal chemistry screening support,...


  • United Kingdom NuChem Sciences Full time

    NuChem Sciences, a Sygnature Discovery business is a world-leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional facilities in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City. Its staff of over 1,000, which includes 900 scientists, partners with global...


  • United Kingdom Metrion Biosciences Ltd. Full time

    Cell Culture Research Associate / Scientist Metrion Biosciences (‘Metrion’) is a UK-based, ion channel focused Contract Research Organisation (CRO) providing high-quality in vitro preclinical drug discovery and safety profiling services. Formed in 2015, Metrion has since established a loyal and growing global customer base who access our...

  • Sales Executive

    3 weeks ago


    United Kingdom george james ltd Full time

    Our client is a global leader in the automation, detection and liquid handling market. Their automated solutions are used across the Genomics, Clinical Diagnostics, basic research and the drug discovery industry. The company seeks a dynamic and motivated UK Sales manager, to implement Sales and Marketing strategies and lead the UK Sales team to achieve...


  • United Kingdom Metrion Biosciences Ltd. Full time

    Research Associate Scientist/Scientist I About Metrion Biosciences Metrion Biosciences (‘Metrion’) is a UK-based, ion channel focused Contract Research Organisation (CRO) providing high-quality in vitro preclinical drug discovery and safety profiling services. Formed in 2015, Metrion has since established a loyal and growing global customer base who...

  • Senior/Principal Scientist

    Found in: Jooble UK C2 - 2 weeks ago


    United Kingdom Cranleigh STEM, Sustainability & SHEQ Recruitment Full time

    We have an exciting opportunity for an experienced scientist to join a growing therapeutics organisation. You will contribute to cutting-edge research in the development of therapeutics for veterinary diseases. The role requires expertise in in vitro assay development, molecular pharmacology, and cell biology. As a Principal Scientist, you must also have a...


  • United Kingdom Metrion Biosciences Ltd. Full time

    Cell Culture Research Associate / Scientist About Metrion Biosciences Metrion Biosciences (‘Metrion’) is a UK-based, ion channel focused Contract Research Organisation (CRO) providing high-quality in vitro preclinical drug discovery and safety profiling services. Formed in 2015, Metrion has since established a loyal and growing global customer base...


  • United Kingdom PharmaGroww Full time

    JOB DESCRIPTION Jubilant Pharma Limited is a global integrated pharmaceutical company offering a wide range of products and services to its customers across geographies. We organise our business into two segments, namely, Specialty Pharmaceuticals, comprising Radiopharmaceuticals (including Radio pharmacies), Contract Manufacturing of Sterile Injectable,...


  • United Kingdom AstraZeneca GmbH Full time

    About AstraZeneca AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a...

  • Join Our Talent Community

    Found in: Jooble UK C2 - 3 weeks ago


    United Kingdom Singular: Building Brilliant Biotechs Full time

    Join the Singular Talent Community || Biotech and Drug Discovery Here at Singular, we work exclusively in the biotech and drug discovery sector. Here's what we can offer you as part of our Talent Community: We provide personalised career coaching designed specifically to help you build a successful biotech career, on your terms. We offer no-obligation CV...


  • United Kingdom Singular: Building Brilliant Biotechs Full time

    Join the Singular Talent Community || Biotech and Drug Discovery Here at Singular, we work exclusively in the biotech and drug discovery sector. Here's what we can offer you as part of our Talent Community: We provide personalised career coaching designed specifically to help you build a successful biotech career, on your terms. We offer no-obligation CV...


  • United Kingdom Nuclera Ltd Full time

    Nuclera is a venture-backed, founder-driven biotech company headquartered in Cambridge, UK with significant operations in Boston, USA. The company’s mission is to make biology accessible to everyone through desktop bioprinting. We are beginning this mission by making proteins accessible through the launch and on-going development of our eProtein desktop...