Research Scientist

4 days ago


Bristol, United Kingdom eXmoor Pharma Concepts Limited Full time

Job title: Principal Scientist
Reporting to: Head of Process Development
Department: Process and Analytical Development
No of Direct reports: 0
Location: Bristol
Summary:
eXmoor helps clients with their manufacturing of cell and gene therapies (CGT) and biopharmaceuticals. We provide:
# translation consultancy to close the gap between R&D and clinical manufacture,
# process development services from our labs in Bristol,
# GMP manufacturing of cell and gene therapies, and
# capital project design through to licensing.

We are looking for a principal scientist to work in our analytical services department with particular expertise in cell-based assay development to support our clients in the clinical development of their cell and gene therapy projects. This is an exciting opportunity to work with eXmoor’s globally recognised team of scientists, consultants and engineers, on a wide range of Client projects in a rapidly growing market.
Job Description:
Job Purpose:
You will provide scientific expertise in assay development, with a particular focus on cell-based assays, to support eXmoor’s cell and gene therapy clients within our process development and GMP manufacturing business. You will be part of a fast-growing analytical services team focusing on analytical development and QC projects using state-of-the-art technologies and in compliance with guidelines related to all aspects of CMC. This is a senior technical role that requires hands-on lab work.
Main areas of responsibility/ key duties:
You will conduct your duties to the highest quality standard and in a safe way, complying with all policies and procedures and with due care and attention for yourself and your peers.
You will provide scientific leadership and be a subject matter expert in analytical development to support the clinical and commercial development of cell and gene therapies.
You will lead the tech transfer of a range of assays from development into QC after being developed both in-house and externally.
You will encourage innovation in the wider team and eXmoor’s business to support eXmoor's technical strategy.
You will contribute to early technical discussions with prospective clients.
You will demonstrate a forward-looking view on technology development in and around your area of expertise to support and develop eXmoor's business objectives.
You will use your experience and draw from, as well as contribute to the literature to refine study objectives and protocols. You will ensure reports, protocols and presentations meet eXmoor’s expected scientific and quality standards.
You will author, review and/or approve study protocols and reports.
You will support business development activities when required.
You will contribute to the success of the wider business by supporting the GMP, TRN and Capital project teams on a range of client and internal projects.
You will ensure compliance with lab documentation including risk assessments, SOPs, COSHH forms, lab notebooks and records.
You will ensure safe working practices and comply with eXmoor QMS and H&S policy.
You will represent eXmoor pharma externally to the broader community through the delivery of technical presentations.
Person Specification:
Essential Qualifications & Experience:
PhD in relevant area + 6 years industry experience or BSc/MSc 10+ years of industry experience, or equivalent years experience.
Established subject matter expert in analytical development with particular expertise in cell-based assays development (such as infectivity, Identity, and potency assays).
Experienced in the development of QC compliant flow cytometry panels for a range of cell therapies assays.
Experience with DoE and statistical analysis. Proficiency with maths and computing, including MS Office and statistics, DoE, and graphing software.
Desirable Qualifications & Experience:
Experience with developing infectivity assays for a range of viral therapies.
Experience coaching and mentoring.
Established network within the ATMP sector.
Patents, publications and conference presentations.
Experience in growing business opportunities.
Competences Required:
Organisation, planning and time management.
Oral and written communication skills.
Leadership and teamworking.
Innovation, inquisitiveness and willingness to learn.
Attention to detail and getting things finished.
Problem solving.
Building constructive relationships and earning respect.
Motivated by growing a bio-technology business in the CGT / biopharmaceutical market.
#J-18808-Ljbffr



  • Bristol, Bristol, United Kingdom Leonardo Full time

    Job OverviewLeonardo is seeking talented scientists and engineers to bridge the gap between theoretical possibilities and practical implementable solutions. This role is ideal for individuals with a background in applied physics, electro-optics, signal processing, or related fields.Key ResponsibilitiesConduct applied research to explore new technologies and...


  • Bristol, Bristol, United Kingdom CellVoyant Full time

    Job OverviewWe are seeking a highly motivated and skilled Machine Learning Research Scientist to join our team at CellVoyant. As a key member of our research group, you will be responsible for advancing the development of our AI models, driving innovation in research and development, and contributing to groundbreaking discoveries.

  • Research Scientist

    3 weeks ago


    Bristol, Bristol, United Kingdom Planet Pharma Full time

    About the RoleAs an Observational Research Scientist at Planet Pharma, you will play a pivotal role in advancing healthcare insights and outcomes by leveraging real-world data (RWD) across various functional areas. You will contribute to designing, planning, and delivering studies that inform decision-making within product teams and therapeutic areas.

  • Researcher - Science

    2 weeks ago


    Bristol, United Kingdom The Developer Link Full time

    Machine Learning Researcher / Scientist - Bristol 1 day per week Hybrid - Flexible Salary - Biotechnology AI ML Start-up TDL have partnered with a ground breaking, funded and globally recognised research based start-up who are attacking never solved before problems in ML solutions for the Genomics / Biotech space.Their work and ML products have the potential...


  • Bristol, United Kingdom The Developer Link Full time

    Machine Learning Researcher / Scientist - Bristol 1 day per week Hybrid - Flexible Salary - Biotechnology AI ML Start-up TDL have partnered with a ground breaking, funded and globally recognised research based start-up who are attacking never solved before problems in ML solutions for the Genomics / Biotech space. Their work and ML products have the...


  • Bristol, United Kingdom The Developer Link Full time

    Machine Learning Researcher / Scientist - Bristol 1 day per week Hybrid - Flexible Salary - Biotechnology AI ML Start-up TDL have partnered with a ground breaking, funded and globally recognised research based start-up who are attacking never solved before problems in ML solutions for the Genomics / Biotech space. Their work and ML products have the...

  • ML Scientist

    8 months ago


    Bristol, United Kingdom CellVoyant Full time

    We are actively searching for a highly motivated and skilled Machine Learning scientist proficient in ML and computer vision, with a keen interest in genomics, microscopy data and their applications. As a Machine Learning scientist, your role will be pivotal in advancing the development of our AI models. This encompasses contributions to research,...


  • Bristol, United Kingdom The Developer Link Full time

    Machine Learning Researcher / Scientist - Bristol 1 day per week Hybrid - Flexible Salary - Biotechnology AI ML Start-up TDL have partnered with a ground breaking, funded and globally recognised research based start-up who are attacking never solved before problems in ML solutions for the Genomics / Biotech space. Their work and ML products have the...


  • Bristol, Bristol, United Kingdom CellVoyant Full time

    Senior Machine Learning ScientistWe are looking for a Senior Machine Learning Scientist to lead our AI development efforts at CellVoyant. As a seasoned expert in machine learning, you will be responsible for driving innovation in our AI models, collaborating with cross-functional teams, and developing cutting-edge methodologies.Key Responsibilities:Research...


  • Bristol, United Kingdom The Developer Link Full time

    Machine Learning Researcher / Scientist - Bristol 1 day per week Hybrid - Flexible Salary - Biotechnology AI ML Start-up TDL have partnered with a ground breaking, funded and globally recognised research based start-up who are attacking never solved before problems in ML solutions for the Genomics / Biotech space. Their work and ML products have the...


  • Bristol, United Kingdom The Developer Link Full time

    Machine Learning Researcher / Scientist - Bristol 1 day per week Hybrid - Flexible Salary - Biotechnology AI ML Start-up TDL have partnered with a ground breaking, funded and globally recognised research based start-up who are attacking never solved before problems in ML solutions for the Genomics / Biotech space. Their work and ML products have the...


  • Bristol, United Kingdom The Developer Link Full time

    Machine Learning Researcher / Scientist - Bristol 1 day per week Hybrid - Flexible Salary - Biotechnology AI ML Start-upTDL have partnered with a ground breaking, funded and globally recognised research based start-up who are attacking never solved before problems in ML solutions for the Genomics / Biotech space. Their work and ML products have the potential...


  • Bristol, United Kingdom The Developer Link Full time

    Machine Learning Researcher / Scientist - Bristol 1 day per week Hybrid - Flexible Salary - Biotechnology AI ML Start-up TDL have partnered with a ground breaking, funded and globally recognised research based start-up who are attacking never solved before problems in ML solutions for the Genomics / Biotech space. Their work and ML products have the...


  • Bristol, United Kingdom Better Placed Ltd - A Sunday Times Top 10 Employer In 2023! Full time

    Research Scientist – AI Innovation Location: Remote / Occasional Travel to The Bay Area Type: Full-time Are you driven to push the boundaries of AI and transform how large language models (LLMs) are built and used?My client, a forward-thinking startup, is developing task-optimized LLMs that deliver exceptional speed, accuracy, and control for enterprise...


  • Bristol, United Kingdom NHS Blood and Transplant Full time

    Job Summary NHS Blood and Transplant is an integral part of the NHS, collecting and processing 2 million blood donations a year. Our Healthcare Scientists provide crucial support to NHS Hospitals, processing, testing and issuing blood and its components and delivering diagnostic and therapeutic services relating to the transfusion of blood and stem...


  • City Of Bristol, United Kingdom The Developer Link Full time

    Machine Learning Researcher / Scientist - Bristol 1 day per week Hybrid - Flexible Salary - Biotechnology AI ML Start-upTDL have partnered with a ground breaking, funded and globally recognised research based start-up who are attacking never solved before problems in ML solutions for the Genomics / Biotech space. Their work and ML products have the potential...


  • City Of Bristol, United Kingdom The Developer Link Full time

    Machine Learning Researcher / Scientist - Bristol 1 day per week Hybrid - Flexible Salary - Biotechnology AI ML Start-upTDL have partnered with a ground breaking, funded and globally recognised research based start-up who are attacking never solved before problems in ML solutions for the Genomics / Biotech space. Their work and ML products have the potential...


  • City Of Bristol, United Kingdom The Developer Link Full time

    Machine Learning Researcher / Scientist - Bristol 1 day per week Hybrid - Flexible Salary - Biotechnology AI ML Start-up TDL have partnered with a ground breaking, funded and globally recognised research based start-up who are attacking never solved before problems in ML solutions for the Genomics / Biotech space. Their work and ML products have the...


  • Bristol, United Kingdom NHS Blood and Transplant Full time

    Job summary NHS Blood and Transplant is an integral part of the NHS, collecting and processing 2 million blood donations a year. Our Healthcare Scientists provide crucial support to NHS Hospitals, processing, testing and issuing blood and its components and delivering diagnostic and therapeutic services relating to the transfusion of blood and stem...


  • Bristol, Bristol, United Kingdom Anaphite Full time

    Company OverviewAnaphite is a pioneering company dedicated to decarbonizing battery production through dry electrode coating technology. Founded in 2018, our mission is to accelerate the energy transition by collaborating with the battery industry to optimize manufacturing processes.We are headquartered in central Bristol, UK, and are committed to building a...