PhD Bioinformatician

6 days ago


London, United Kingdom Esox Biologics Full time

Title:  Bioinformatician, 40 hours per week – BI002. 
Compensation: £38-65,000 plus equity, pension, health insurance and free lunch
Esox  Biologics is a bio-tech company ensuring food security by improving the efficiency of aquaculture. We do this by preventing the spread of infectious diseases among aquatic animals. Aquaculture is the fastest growing food production sector yet aquatic veterinary medicine lacks innovative tools to detect and prevent the spread of aquatic pathogens. With more than ninety percent of aquatic microorganisms uncharacterised and undescribed by science, our Detect platform harnesses metagenomics to resolve this biological dark-matter to reduce mortalities in aquaculture. 

Role:  We are hiring a Bioinformatician to join our Detect team in an office-based role. Stored and visualized through our web-app, this data advances their understanding of aquatic ecosystems. Alongside the lead bioinformatician, you will be writing and maintaining our bioinformatics and cloud computing workflows, introducing automation and transparency throughout. Additionally, you will be generating insights that support our R&D and product development programmes and working with client data. This role would suit a candidate that would be interested in combining periods of focused pipeline development with periods of pipeline maintenance and meeting ad-hoc bioinformatics requirements. Team:  Esox Biologics is a tight-knit and highly collaborative team of scientists, engineers and creatives with a passion for translating innovative technologies into real-world solutions. Backed by private equity and generating revenue, Esox Biologics has established its position within aquaculture by transforming existing knowledge of aquatic microbiomes. You will be the company’s second full-time bioinformatics hire. 

Work with your team to maintain and continually develop our bioinformatics pipelines for processing sequencing data, compiling our database and generating metagenomic insights. 
·  Work with your team to build and maintain a MAG assembly pipeline that integrates into our long-read sequencing platform. This pipeline will enable the assembly of viral, prokaryotic and eukaryotic genomes.
· Data management:  Work with your team to   extend our existing Azure infrastructure to store a growing collection of sequenced reads, contigs, MAGs, and associated metadata.  
· Collaboration with lab team:  Work in close collaboration with the lab team to ensure data generated from the bioinformatic pipelines is experimentally validated.
· Essential  – A degree in Computational Biology/Genomic Science/Bioinformatics or equivalent discipline is essential. Essential – Experience developing reproducible bioinformatics workflows, ideally using Python and Snakemake, including automated testing.
· Essential  – Experience writing clear code and documentation such that work can be traced, replicated and reproduced.
· Highly Desirable - Experience with quality control of Nanopore sequencing data.
· Desirable – Experience managing growing biological databases.
· Desirable  – A passion for aquaculture, aquatic organisms, and sustainable food systems. 

Must-Have:  Python/Git/Bioinformatics workflow development/Conda
· Pytest/GitHub Actions/Nanopore QC/R
· Nice-to-Have:  Assembly, Binning & Annotation/Azure computation and storage/Quarto/Docker/SQLAlchemy

Initial video call with one of the team
· Chat with lead bioinformatician
·


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