Medical Sciences Director

Novartis has a long term commitment to Global Health including communicable diseases like malaria and non communicable diseases. Novartis first supported sickle cell disease (SCD) care over 50 years ago with the development of chelators for the management of iron overload. Novartis BioMedical Research (BR) is the innovation engine of Novartis that collaborates across the company and beyond, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Translational Medicine (TM) is the clinical research arm of BR and includes about 900 associates globally. TM plays a pivotal role in bringing innovative medicines to patients, by building on research advances to develop new therapies, and bridging drug discovery and clinical application.
The TM Discovery & Profiling (TMDP) is a group of physicians and clinical researchers who drive innovative science from discovery to the patient through the selection, profiling, and effective development of medicines. Translational medicine experts oversee Phase 1 and 2 clinical trials to demonstrate early safety and efficacy, as well as support for Phase 3 development through clinical pharmacology profiling studies. Translational medicine experts are key and highly visible members of global cross-functional project teams that design and implement early research and discovery projects, that then culminate in clinical trails. Translational medicine experts collaborate with colleagues in biology and chemistry to identify targets in diseases with significant unmet medical needs and provide input on likely clinical development pathways. The studies led by our translational medicine experts are among the most critical steps in drug development at Novartis.
As a TM Expert for Global Health, you will collaborate with the Therapeutic Area Head or other experienced TM Experts to develop high value decision-strategies for the Translational Medicine component of drug development projects and lead global cross-functional project teams.
This is a hybrid role requiring on-site presence at the Westworks London office three days a week.
this includes assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications and other relevant activities
Lead global project teams through early phase development, participate in project teams through program life cycle
Acts as medical monitor for one or more clinical studies
Communicate clinical team matters to project teams and relevant decision boards (Disease Area Decision Board).
Oversee publication and external presentation of clinical study results
work closely with biomarker experts in implementation
Participate in team presentations to Health Authorities as TM Expert
Doctoral degree, MD required with clinical subspecialty training preferred in one of the following areas: Hematology or Pediatrics with Sickle Cell expertise; Additional PhD/post-doctoral equivalent research preferred as well as board-certification in relevant subspecialty area.
At least 1-2 years’ experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience; Demonstrated interest/experience in Global Health
Recognized for medical expertise.
Recognized for scientific expertise: respected by colleagues internally and externally, have made significant contributions to the field and created / established new concepts; record of high quality publications in international scientific journals.
Able to work independently on study planning and execution, and with supervision on project planning.
Additional consideration for candidates with advanced research experience in data science,
Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. Commitment to Diversity and Inclusion : Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: