Senior Scientist

3 weeks ago

Cambridge Cambridgeshire, United Kingdom ROYAL SOCIETY OF CHEMISTRY Full time

CK Group are working in partnership with Nxera Pharma UK Limited (formerly Sosei Heptares) to recruit a lab-based Senior Scientist in Protein Binder Discovery based in Granta Park, Cambridge.

Company:
Nxera Pharma is a technology powered biopharma company, in pursuit of new specialty medicines to improve the lives of patients with unmet needs in Japan and globally, focused on therapeutic areas in inflammation diseases, neurology and immunology.


The Role:
The successful candidate will join the Protein Binders Discovery Team at Nxera Pharma and will also be part of the wider Biochemistry and Biophysics teams. The successful candidate will use phage display expertise to select protein binders against therapeutic membrane protein targets to enable structure determination and drug discovery efforts.


The role will include the following responsibilities:
  • Screening phage display libraries against membrane protein targets
  • Protein engineering of VHH frameworks
  • Subcloning of plasmid constructs for expression
  • Biophysical evaluation of VHH hits
Your Background:
  • PhD (or MSc with equivalent lab experience) in a relevant area of biology
  • Theoretical and practical expertisein phage display technologies and selection techniques
  • Experience working with phage antibody libraries and preferably VHH display
  • Strong and evidenced molecular biology proficiency
  • Experience of screening techniques (eg ELISA, cell binding assays etc)
  • Experience of affinity maturation
  • Analytical thinking and good problem-solving skills
DESIRABLE:
  • Experience of measuring affinity using either BLI or SPR
  • Experience of library build (either affinity maturation or immunised, naïve or synthetic libraries)
  • Experience in working with membrane proteins (in particular GPCRs)
  • Computational expertise focussed around protein binder design would be advantageous

Apply:
It is essential that applicants hold entitlement to work in the UK. Please quote job reference 99230 in all correspondence. #J-18808-Ljbffr

  • Senior Scientist

    2 days ago

    Cambridge, Cambridgeshire, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, Onsite Is this the role you are looking for If so read on for more details, and make sure to apply today. POSITION TITLE: Senior Scientist DEPARTMENT: Research & Development LOCATION: Cambridge, On-site. Brief Description : The Senior Scientist will provide immunology and biology knowledge to define and support the...

  • Senior Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Pure Life Sciences Full time

    Job Description Senior Scientist, Cambridge, Onsite POSITION TITLE: Senior Scientist DEPARTMENT: Research & Development LOCATION: Cambridge, On-site. Brief Description: The Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics. ...

  • Senior Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, Onsite POSITION TITLE: Senior Scientist DEPARTMENT: Research & Development LOCATION: Cambridge, On-site. Brief Description : The Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics. Desired Skills...

  • Senior Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, Onsite POSITION TITLE: Senior Scientist DEPARTMENT: Research & Development LOCATION: Cambridge, On-site. Brief Description : The Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics. Desired Skills...

  • Senior Scientist

    1 month ago

    Cambridgeshire, United Kingdom Hyper Recruitment Solutions Ltd Full time

    We are currently looking for a Senior Bioanalytical Scientist to join a leading Pharmaceutical company based in the Cambridgeshire area for an initial 12 months. As the Senior Bioanalytical Scientist you will be responsible for taking a lead role designingbioanalysis method strategies and interpreting data generated in support of new modality projects. This...

  • Senior Computational Scientist

    2 days ago

    Cambridge, Cambridgeshire, United Kingdom SRG Full time

    I am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist. Do not wait to apply after...

  • Senior/Laboratory Research Scientist

    4 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, Onsite Senior Scientist Research & Development The Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics. Academic/Major: ~ PhD in Molecular or Cellular Biology, Biomedicine, Immunology or...

  • Senior/Laboratory Research Scientist

    4 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, Onsite Senior Scientist Research & Development The Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics. Academic/Major: ~ PhD in Molecular or Cellular Biology, Biomedicine, Immunology or...

  • Senior Scientist

    2 months ago

    Cambridge, Cambridgeshire, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits. Who we are We are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior Data Scientist

    4 days ago

    Cambridge, Cambridgeshire, United Kingdom Kemioconsulting Full time

    Passion for developing and applying maths and statistics to biological problems? 15th May, 2024 (Senior) Data Scientist Cambridge (Hybrid – 2 days in office) Must have right to work in the UK Founded 5 years ago this Cambridge based biotech are developing revolutionary genomic technologies that improve the lives of cancer patients through early...

  • Senior Data Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Kemioconsulting Full time

    Passion for developing and applying maths and statistics to biological problems? 15th May, 2024 (Senior) Data Scientist Cambridge (Hybrid – 2 days in office) Must have right to work in the UK Founded 5 years ago this Cambridge based biotech are developing revolutionary genomic technologies that improve the lives of cancer patients through early...

  • Senior Research Scientist

    2 months ago

    Cambridge, Cambridgeshire, United Kingdom Joynes & Hunt Full time

    Senior Research Scientist-CMC, process development Our client is a biotechnology research company. They are currently seeking a driven and organised senior research scientist to join their preclinical development team. This is an exciting opportunity for an enthusiastic candidate to work with this team to progress a leading microbiome company into clinical...

  • Senior Scientist

    7 days ago

    Cambridge, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, OnsitePOSITION TITLE: Senior ScientistDEPARTMENT: Research & DevelopmentLOCATION: Cambridge, On-site.Brief Description :nThe Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics.Desired Skills and...

  • Scientist/Senior Scientist, Technology Development

    2 months ago

    Cambridge, Cambridgeshire, United Kingdom Garuda Therapeutics, Inc. Full time

    Garuda Therapeutics is pioneering the development of off-the-shelf hematopoietic stem cell (HSC)-based cellular therapies for treating patients with blood, bone marrow, immune, and metabolic disorders. The company uses state-of-the-art technologies in developmental biology, gene-editing, stem cells, and mechanobiology to engineer safe, compatible HSCs in...

  • Senior Scientist

    2 weeks ago

    Cambridge, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, OnsiteBelow covers everything you need to know about what this opportunity entails, as well as what is expected from applicants.POSITION TITLE: Senior ScientistDEPARTMENT: Research & DevelopmentLOCATION: Cambridge, On-site.Brief Description:The Senior Scientist will provide immunology and biology knowledge to define and support...

  • Senior Scientist- Pipeline Scientist

    4 weeks ago

    Cambridge, United Kingdom Reed Scientific Full time

    **(Senior) Scientist - Pipeline Scientist** REED are working with an exciting life sciences start-up based in the Cambridge area to fill a vacancy for a Scientist/Senior Scientist to join their TCR expression pipeline team. **In this role you will be responsible for**: - Microfluidic-based NGS library preparation - Work with technology development,...

  • Senior Scientist

    2 weeks ago

    Cambridge, United Kingdom Pure Life Sciences Full time

    Job DescriptionSenior Scientist, Cambridge, OnsitePOSITION TITLE: Senior ScientistDEPARTMENT: Research & DevelopmentLOCATION: Cambridge, On-site.Brief Description:The Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics.Desired Skills...

  • Senior Scientist

    2 weeks ago

    Cambridge, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, OnsitePOSITION TITLE: Senior ScientistDEPARTMENT: Research & DevelopmentLOCATION: Cambridge, On-site.Brief Description:The Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics.Desired Skills and...

  • Senior Scientist

    2 weeks ago

    Cambridge, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, Onsite POSITION TITLE: Senior Scientist DEPARTMENT: Research & Development LOCATION: Cambridge, On-site. Brief Description : The Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics. Desired Skills and...

  • Senior Scientist

    2 weeks ago

    Cambridge, United Kingdom Pure Life Sciences Full time

    Senior Scientist, Cambridge, OnsitePOSITION TITLE: Senior ScientistDEPARTMENT: Research & DevelopmentLOCATION: Cambridge, On-site.Brief Description:The Senior Scientist will provide immunology and biology knowledge to define and support the experimental efforts of the R&D team by developing novel approaches to test new biologics.Desired Skills and...