Lead Scientist R&D Process Development

2 weeks ago

Slough Berkshire, United Kingdom Lonza Biologics Porriño SLU Full time

Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

We are currently looking for a Lead Scientist - R&D Process Development to join our Centre of Excellence for biopharmaceutical process development and small-scale GMP manufacturing in Slough, UK.

The purpose of the role is to maintain Lonza Pharma & Biotech as a leading contract manufacturer through the development and optimization of new mammalian cell culture technologies. This role would design, implement and maintain automation engineering solution for research and developmental lab scale with an aim of developing next generation process that meet industry demands and maintain Lonza as the lead supplier.

Key responsibilities:

  • Working closely with the upstream R&D team; plans and executes several complex (non-routine) lab & Pilot scale fed batch and perfusion bioreactor process development and optimization experiments
  • Hands on expertise at using and troubleshooting
    • automation solutions like DeltaV
    • configure & program integrated control system like PLCs, DSCs, and SACA
    • control loop feedback like PID controllers
    • automated bioreactor sampling systems
  • Generates experimental results and reviews respective scientific documentation
  • Is responsible for ensuring that studies are scientifically sound and in line with current regulatory guidance and expectations
  • Helps with ensuring lab procedures are adhered to and supports safety assessments
  • Perform other duties as assigned
  • Design, develop, and implement automated systems to optimize upstream bioprocessing workflows.
  • Collaborate with cross-functional teams to understand process requirements and translate them into efficient automation solutions.
  • Lead and work collaboratively across departments with automation design and lead electrical engineers, communicate openly, and foster a learning environment for the team
  • Design, implement and maintain automation engineering solution across various scales bioreactor
  • Assist in the installation, operation, maintenance and repair of automated process and facility equipment and control systems
  • Support equipment startup, commissioning, and qualification activities
  • Work in close collaboration with IT/OTI/Network Infrastructure and Security Teams to ensure a reliable and secure automated manufacturing environment
  • Support updates to and maintenance of data historian systems
  • Familiarity with Biopharma 4.0 digitalization
  • Complying with the required relevant Lonza training

What we need you to have:

  • BSc / MSc / BEng / MEng Field of Study Industrial Controls / Automation / Electrical Engineering / Bioprocessing / Chemical Engineering or similar field
  • Experience inbiotech/pharmaceuticalsetting up automation, instrumentation and controls at least 5-6 years
  • Broad and detailed technology competence in cell culture procedures and handling HTP formats like microplates, deep well plate, shake flask, ambr15
  • Demonstrated innovative skills and experience with leading complex technology projects.
  • High level of communication and presentation skills.

Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

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