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Senior scientist

2 months ago

London, United Kingdom IMU Biosciences Full time

About us

Our immune system plays a central role in maintaining our health and well-being. Understanding its complexity has led to the development of some of the most innovative and exciting therapies. Our mission at IMU Biosciences is to characterise and understand the granular structure of the immune system, and to use that knowledge to improve human health through (i) the advancement of precision medicine, (ii) the development of diagnostics that enable earlier detection of disease, and (iii) the identification of more effective methods of targeting the immune system to treat disease.

We are a multidisciplinary team of world-leading scientists, software engineers, and statisticians who are passionate about changing the face of medicine by leveraging the power and insight of the immune system. Our work lies at the interface of high-throughput immune profiling and machine learning to understand the complexity of the immune system across health and disease. We are a diverse team in an early-stage startup that values creativity and innovation, offering a dynamic environment where your ideas can truly make an impact on health outcomes.

About the job

As a Senior Scientist in the Discovery team you will be responsible for analysis and interpretation of deep immunophenotyping experiments, supporting innovation in IMU’s proprietary immune mapping platform and delivering client projects. The role will rely on both a solid understanding of immunological science and a strong proficiency in data science approaches, using these skills to proactively drive projects forward. Given the interdisciplinary nature of the role, the candidate will be able to collaborate extensively across the company, especially with members of our R&D, Data Science and Engineering teams. As it is primarily a data science role, this position will not require routine wet lab work, but prior experience in flow cytometry and handling of human samples will be valuable. IMU also employs a hybrid working policy that will require regular onsite working in central London.

Skills, knowledge and experience

Essential Criteria

  • PhD in a relevant area such as basic, translational or systems immunology, with 3+ years of post-doctoral or industry experience
  • Strong background in immunological research and awareness of the current state of the field, including emerging trends
  • Proficiency in data processing, advanced statistical analysis and data visualisation in R
  • Competency with git/github and reproducible coding practices
  • Experience running and/or building bioinformatics pipelines
  • Curation and interrogation of large biological datasets (e.g. flow cytometry, transcriptomics, clinical metadata)
  • Experience in multi-parameter flow cytometry or mass cytometry
  • Strong foundational scientific skills, including experimental design and interpretation, critical thinking and strategic decision-making
  • Excellent communication skills and ability to collaborate effectively across multidisciplinary teams
  • Right to work in the United Kingdom

Desirable Criteria

  • Experience handling multiomics data 
  • Familiarity working with human blood and tissue samples
  • R package development and maintenance
  • Scientific publications showcasing your data science skills
  • Experience with patent filings

Responsibilities

  • Perform rigorous and biologically-informed systems immunology analysis of internal and external immunophenotyping datasets
  • Design and coordinate experiments to drive innovation of IMU’s immune mapping engine
  • Collaborate closely with data scientists to support design and interpretation of advanced statistical and machine learning-driven IMU platform output
  • Provide expert advice to other teams based upon an up-to-date awareness of the field of immunology
  • Contribute to preparation of summary reports and presentations
  • Contribute to manuscript preparation and publication

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope, purpose and grading of the post.

Benefits

  • Fast-paced startup culture where everyone’s perspective truly matters
  • Career development support e.g. training courses, scientific conferences
  • Excellent opportunities for advancement as the company grows
  • Brand new state of the art facilities in central London
  • Working on cutting edge of translational research
  • Embedding in a talented multidisciplinary team
  • Competitive salary based on experience