Group Lead
7 days ago
Overview
We are seeking a skilled and motivated individual to lead an interdisciplinary team in developing the next generation of mammalian expression systems and cell lines. The ultimate goal is to enable highly productive pharmaceutical bioprocesses and contribute to the advancement of cost-effective immunotherapeutics.
Key Responsibilities
As the Group Lead for Cell Line Development, your primary duties will include:
- Leadership & Team Management:
- Plan and oversee work packages to ensure key deliverables are achieved within defined timeframes.
- Manage a team of scientists with diverse expertise, including analytical development, vector design, and small-scale bioreactor screening.
- Conduct regular one-on-one meetings with team members to review progress, troubleshoot challenges, and support professional development.
- Collaboration & Communication:
- Foster an open and collaborative working environment by closely partnering with other group leads and team members.
- Prepare and deliver presentations to internal stakeholders and project teams, and actively participate in group meetings.
- Laboratory Work & Documentation:
- Spend approximately 50% of your time on lab-based activities.
- Ensure all experimental work is recorded to a high standard, maintaining data integrity and accuracy.
- Author Standard Operating Procedures (SOPs), training documents, and risk assessments.
- Document findings in lab notebooks and support the preparation of health and safety protocols.
- Training & Development:
- Train team members to ensure a high level of technical competence and compliance with quality standards.
- Provide mentorship to support both technical growth and career development.
- Operational & Maintenance Responsibilities:
- Participate in routine laboratory maintenance, equipment upkeep, cleaning schedules, and consumables management.
- Share responsibility for out-of-hours cell culture maintenance as required.
- Continuous Improvement:
- Stay informed of relevant scientific advancements and emerging technologies to identify opportunities for process optimization and cost reduction.
Qualifications & Experience
Minimum Requirements:
- Education:
- Bachelor’s or Master’s degree in Biochemistry, Molecular Biology, or a related field.
- Bachelor’s/Master’s degree with 5+ years of industry experience, or PhD with 3+ years of relevant experience.
- Technical Expertise:
- Proficiency in CHO cell line development within the biopharmaceutical industry.
- Skilled in executing analytical methods such as HPLC/UPLC and LC-MS for antibody characterization.
- Experience with high-throughput and automated technologies for mammalian cell line generation (e.g., Beacon, deep well plates, Ambr15 systems).
- Hands-on experience with gene editing, single-cell cloning, CRISPR, and ORF library screens.
- Familiarity with plasmid design for stable and high-level expression of therapeutic antibodies, including bi-/tri-specific formats.
- Competence in molecular and cell biology techniques, such as FACS, qRT-PCR, Western blotting, and ELISA.
- Application of Design of Experiments (DOE) for experiment planning and optimization.
- Experience in screening clonal cell lines for batch, fed-batch, and perfusion bioreactor systems.
- Proficiency in optimizing fed-batch methods for antibody production.
- Experience working with CHO and HEK293 cell lines in bioprocess settings.
Desirable Experience:
- Working with large datasets, including transcriptomics and proteomics.
- Techniques such as mammalian cell culture, transfection, nucleofection, and genotyping.
- Familiarity with 3rd-generation lentiviral plasmid systems in a CAT2.0 environment.
Skills & Attributes
- Analytical mindset with advanced problem-solving skills.
- Ability to manage multiple priorities with excellent time management and organizational skills.
- Strong written and verbal communication skills.
- Proactive, dependable, and detail-oriented.
- A team player who thrives in a dynamic, multidisciplinary environment.
- Passionate about innovation and continuous improvement
-
Group Lead
3 days ago
Oxfordshire, United Kingdom Hyper Recruitment Solutions Ltd Full timeWe are currently looking for a Group Lead to join a growing biotechnology organisation based in the Oxfordshire area. The company are involved with developing ground-breaking biological solutions to sustainably and safely control insects that transmit disease and destroy crops. As the Group Lead you will be responsible for mass rearing of our agricultural...
-
Lucy Group's Treasury Lead
2 weeks ago
Oxford, Oxfordshire, United Kingdom Lucy Group Ltd Full timeJob SummaryLucy Group Ltd is recruiting a seasoned Treasury Lead to manage its treasury department.The successful candidate will develop and implement the group's treasury strategy and roadmap, while empowering the treasury team through advanced communication skills and management style.
-
Group Lead, Numerical Physics
7 months ago
Oxfordshire, United Kingdom First Light Fusion Full time**Responsibilities will include**: The Numerical Physics Group Lead, with their team, will determine, implement, and improve physics models, numerical algorithms, and code features, in cooperation with theoretical physicists, model validation analysis, and software engineers. Extensive model verification testing and cross-code comparison will be used to...
-
Model Validation Group Lead
7 months ago
Oxfordshire, United Kingdom First Light Fusion Full time**Responsibilities will include**: The Model Validation Group Lead, with their team, will perform simulations of both internal and external experiments to determine the validity and impact of modelling choices and assumptions, by comparison of simulation data to experimental data. Model validation requires working closely with experimental physicists to...
-
M4 Mechanical Design Group Lead
7 months ago
Oxfordshire, United Kingdom First Light Fusion Full timeFirst Light Fusion are designing the world’s largest pulsed power machine, Machine 4. This will be a circa 100MJ, multi-megavolt, short pulse machine capable of driving currents in excess of 45 MA in our loads. The primary purpose of this machine will be to electro-magnetically launch hyper-velocity projectiles in order to test FLF’s novel ‘projectile...
-
Group Financial Controller
2 weeks ago
Oxfordshire, United Kingdom Marc Daniels Full timeA global market leading group are looking for a talented Group Financial Controller to join their finance team. As a key member of the leadership team, you will play a pivotal role in shaping the financial strategy and operations of a large international group, a recognized leader in the global market. The person in this role will lead team of group finance...
-
Group Accountant
21 hours ago
Oxfordshire, United Kingdom T2M Resourcing Ltd Full time**Group Accountant - Hybrid** **Oxfordshire** This hybrid role would require the Group Accountant to be in the office 2 to 3 days per week, and provide accurate recording, and reporting of accounting information whilst supporting continuous improvement to ensure smooth processing of transactions. **Responsibilities of the Group Accountant**: -...
-
Group Financial Controller
5 hours ago
Oxfordshire, United Kingdom Axiom Executive Full timeOur client is an international health business with ambitious growth plans. Reporting into the CFO the Group Financial Controller will be responsible for both internal and external Financial Reporting taking responsibility and ownership for the implementation of appropriate policies, procedures, and processes to ensure an effectivecontrol environment. You...
-
Group Exercise Program Director
2 weeks ago
Oxford, Oxfordshire, United Kingdom PureGym Group Full timeAbout the Role:\We are seeking a highly motivated Group Exercise Program Director to join our team at PureGym Group. The successful candidate will be responsible for managing and improving group exercise offerings within the gym, and providing ongoing training and professional development opportunities for fitness staff.\This is a unique opportunity to join...
-
GAP Group LTD | Events Project Manager
2 weeks ago
Oxford, Oxfordshire, United Kingdom GAP Group LTD Full timeComplete your application using the "Apply" button, this will take you directly to the GAP website. Our team is the best in the industry - is it time for you to join us? The Role: Our Events Division combines the expertise of all GAP divisions to provide a one stop shop to supply the Events industry across the UK with all their equipment requirements. ...
-
Group Treasury Manager
1 month ago
Oxford, Oxfordshire, United Kingdom Lucy Group Full timeJob Title: Group Treasury ManagerSalary: £60,000 - £80,000 per annumAbout the Company: Lucy Group is a leading international organization with a presence in Oxford. We are seeking an experienced Group Treasury Manager to join our team.Job Description:The successful candidate will be responsible for delivering the overall group Treasury strategy and...
-
Group Financial Accountant
21 hours ago
Oxfordshire, United Kingdom Marks Sattin recruitment Full timeMarks Sattin is proud to be working with a global consulting firm based in Oxford who are currently on the lookout for a Group Financial Accountant. This role based in Oxford (Hybrid - 1 day office based per week) is a 6 month FTC that will suit individualsthat are fully ACA/ACCA/CIMA qualified with a background in group reporting/accounting. You will take a...
-
Nursery Group Supervisor
4 weeks ago
Oxford, Oxfordshire, United Kingdom Hadland Care Group Full timeNursery Group Supervisor Job DescriptionThis role is suitable for someone with experience in childcare who wants to take on a leadership position. The successful candidate will oversee the care and development of pre-school children in a nursery setting.Job Overview:The Nursery Group Supervisor will lead a team in the nursery, ensuring the smooth operation...
-
Head of Legal
5 days ago
Oxford, Oxfordshire, United Kingdom Lucy Group Full time**Job Overview**Lucy Group is a multinational private company based in Oxford, UK. The group has around 2,000 people across five continents and a turnover exceeding £400m.We're seeking an experienced Head of Legal to lead our legal team, providing expert support to stakeholders across the business. The role requires advanced leadership skills and a deep...
-
Group Financial Accounting Manager
4 hours ago
Oxfordshire, United Kingdom EllisKnight International Recruitment Full timeGroup level Financial Accountant with Consolidation accounting experience required for major publishing organisation. With ownership of the consolidated month end results, annual forecasts and budgets, taxation, as well as producing all statutory reporting requirements for the group. The role will maintain control of all group reporting; ensure compliance...
-
Interim Group Financial Controller
19 hours ago
Oxfordshire, United Kingdom Search Consultancy Full timeSearch Consultancy Ltd is currently looking to recruit an experienced interim Group Financial Controller to support our client through a period of maternity. The role is to start in June and will initially be for 12 months. Based near Oxford our client is operatinga fully hybrid working model so the successful professional can split between the office and...
-
The AA Group | Mobile Vehicle Technician
2 weeks ago
Oxford, Oxfordshire, United Kingdom The AA Group Full time €44,000Mobile Vehicle Technician Better hours, better pay, join the AA. Enjoy work-life balance with weekday shifts covering hours between 8am and 8pm with overtime available on the end of your shift and on Saturdays. The role of a Service Maintenance and Repair Technician is multifaceted and impactful, and due to a successful year we are expanding the team....
-
Informatics Support
4 days ago
Oxfordshire, United Kingdom Hyper Recruitment Solutions Ltd Full time**Informatics support - Group Manager** **Oxfordshire** HRS are working with a world leading global platform business who's innovative technologies have consistently aided in the development of life changing pharmaceutical products across multiple therapeutic areas. Operating globally, they are currently seekingto hire a Group manager to lead the UK...
-
Senior Software Engineering Group Lead
1 week ago
Oxford, Oxfordshire, United Kingdom Corehr Full timeAs a Senior Software Engineering Group Lead at Corehr, you will play a key role in the development of our innovative OpenSAFELY platform.We are seeking an experienced software developer to lead our fast-growing engineering team and provide line management, training, technical advice, mentorship, and coaching to colleagues.The successful candidate will have...
-
Diagnostic and Fusion Engineering Group Lead
2 days ago
Abingdon, Oxfordshire, United Kingdom UK Atomic Energy Authority Full time €65,000Diagnostic and Fusion Engineering Group Lead A high number of candidates may make applications for this position, so make sure to send your CV and application through as soon as possible. Abingdon Rd, Culham, UK Full-time Salary: £67,023 (inclusive of MPP) + excellent benefits including outstanding pension Division: Plasma Science and Fusion...