Head of PBPK

3 weeks ago


Hoddesdon Hertfordshire, United Kingdom Pharmaron Full time

To continue our growth as a premier Contract Research Organisation, we are looking to recruit a PBPK leader to join our organisation. In this new global role, you will lead on delivery of PBPK business through provision of PBPK modelling and simulation science and strategy from projects in the discovery phase through to the clinic. Through building further capability and devising business plans you will have opportunity to lead on the delivery of PBPK across Pharmaron.
You will work primarily alongside UK Drug Discovery and China based teams but also collaborate with other business units to offer expanded integrated services.
This role will further develop overall Pharmaron capabilities and enhance the reputation of Pharmaron with its scientific and commercial stakeholders.
Opportunities to develop your skills and yourself - our rapid growth brings greater opportunities for you to learn and grow faster
Work with global DMPK Leadership Team to deliver PBPK business strategy for global Pharmaron including contracts, recruitment, software and business model
Lead, design and deliver PBPK modelling and simulation contracts to support Pharmaron business units from Discovery through to clinical development.
Use own expertise in addition to providing mentoring, training and support ensuring PBPK contracts can be delivered to a high standard and in a timely manner
Build the reputation of Pharmaron in PBPK through publications, conference/webinar presence and working with BD & marketing.
Troubleshoot and overcome problems in projects across the Pharmaron organization through use of own technical knowledge and experience
Deliver clear presentations on plans, data and achievements to external partners and internal stakeholders.
Extensive and demonstrable experience in conducting PBPK modelling and simulation work to support the pharmaceutical industry in discovery and/or development activities with solid understanding of related disciplines
Demonstrated impact in scientific leadership applied to drug discovery and development gained from at least 10 years experience in the industry
Minimum BSc level qualification in a relevant scientific discipline with a history of publication and presentations.
In depth knowledge and experience of PBPK principles, application and software packages such as Gastroplus, SimCYP
Demonstrated understanding of drug developability properties and risk mitigation strategies, for example DDI, formulation assessment
Excellent communication, both written and oral, with the ability to influence and to effectively communicating across multiple formats including face to face and virtual project team environments
Our Company: "We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world's leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges".
We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We offer a competitive salary and a progressive and comprehensive suite of employee benefits.
We offer the opportunity for growth and development and will support funding for relevant training and development programmes.
This is an opportunity for you as PBPK leader to make a real impact in a highly scientific and dynamic environment, demonstrate leadership, ambition and the desire to drive forward and embed PBPK into the business.
Founded in 2004, Pharmaron has invested in its people and facilities having established diverse drug R&D service capabilities, ranging from synthetic, medicinal, and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry and isotopically labelled metabolism, chemical & pharmaceutical development to clinical development.


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