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Data Scientist
1 month ago
Data Scientist, Centre for Target Validation External Advertising End Date Advertising End Date:
~ Data Scientist, Centre for Target Validation
Future progression is based on annual performance review.
Support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here .
Duration of Contract : Fixed Term for 2 years
Hours per week : 35 hours per week (Full Time)
W e are seeking to appoint a Data Scientist to join the Centre for Target Validation at the ICR. The postholder will use machine learning / AI and other bioinformatics approaches to identify/develop patient hypotheses, explore target/tumour links and discover biomarkers. The successful applicant will work on the application and development of machine learning/AI tools for the integration of multi-omics patient-derived data (e.g. RNA/DNA/Ribo-seq/proteomics) with patient survival outcomes, cell line model data (e.g. DepMap sensitivity and chemogenomics screens) and target ligandability potential (Chemistry and 3D structure assessments). The data integration via machine learning has the potential to generate novel patient hypotheses for drug discovery projects, not achievable from analysis of the component datasets.
Work experience in relevant research areas is required, preferably focused on cancer biology. Typically, candidates holding a PhD qualification and some work experience will be suitable for this role.
The Centre will deliver bespoke, hypothesis-driven data packages to support decision-making for launch of a drug discovery project. The Centre’s dedicated resources, including biology, functional genomics, assay sciences, chemistry, and bioinformatics teams, will support joint project teams that combine the deep biological and therapeutic knowledge of ICR investigators with the validation and technical expertise of drug discovery scientists. The Centre for Target Validation will serve as a hub, connecting researchers to expertise and resources that will validate and streamline robust, targets into drug discovery programmes in the ICR’s Cancer Therapeutics Unit or into collaborative programmes with external commercial therapy discovery partners.
The CCDD’s exciting goal is to discover high quality small molecule drug candidates and to progress these to clinical trial. All the scientific disciplines are in place to make this possible, including medicinal chemistry, biology, structural biology, assay scientists, drug metabolism and clinical specialists. The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.
We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview.
