Principal Scientist

4 weeks ago

Reading, United Kingdom Cranleigh STEM, Sustainability & SHEQ Recruitment Full time

We have an exciting opportunity for an experienced scientist to join a growing therapeutics organisation. You will contribute to cutting-edge research in the development of therapeutics for veterinary diseases. The role requires expertise in in vitro assay development, molecular pharmacology, and cell biology. As a Principal Scientist, you must also have a strong leadership background.


Key Responsibilities:

  • Implement cutting-edge pharmacological and immunological assays to characterize antibody candidates and assess their therapeutic potential.
  • Collaborate closely with cross-functional teams, including molecular biologists, protein engineers translational scientists and our dedicated CMC Group, to advance drug discovery programs from target validation to clinical development.
  • Provide scientific leadership and guidance to project and laboratory teams as an expert in the field, fostering a culture of innovation, scientific rigor, and excellence.
  • Present research findings and project updates to internal stakeholders, external collaborators, and scientific conferences.
  • Be at the cutting-edge of emerging trends, technologies, and advancements in the fields of in vitro assay development and execution.
  • Guide a multidisciplinary laboratory team to design, produce and test biological candidate antibodies for veterinary use
  • Drive innovation and implement novel approaches, methodologies, and technologies to enhance drug discovery and development efforts through continuous improvement.
  • Contribute to the scientific community through publications, presentations, and participation in scientific forums.
  • Drive antibody discovery efforts through target identification, antibody generation, and lead optimization strategies.


Qualifications/Experience:

  • Ph.D. in Pharmacology, Immunology, Molecular Biology, or equivalent with a minimum of 10 years of industry experience in in vitro pharmacology in drug discovery, preferably with significant antibody experience.
  • Proven track record of scientific leadership and expertise in pharmacology, antibody development, and preclinical drug discovery.
  • Strong background in immunology, cell biology, and molecular biology techniques relevant to antibody discovery and characterization.
  • Demonstrated ability to lead and mentor scientific teams, drive collaborative research efforts, and communicate effectively across interdisciplinary teams.
  • Excellent problem-solving skills, analytical thinking, and ability to thrive in a dynamic and fast-paced research environment.
  • Proficiency in data analysis software, statistical methods, and bioinformatics tools for data interpretation and visualization.
  • Ability to work as an expert cross-functionally, working with colleagues in discovery, early development, clinical and manufacturing.
  • Ability to communicate at all levels within the organisation and act as an advocate for the company with external collaborators and partners.
  • Highly competent across cell-biology, in vitro pharmacology and in vitro assay disciplines with specific expertise in analytical software tools, data analysis and interpretation.



This is an exciting and demanding role for an ambitious individual looking to learn, grow and contribute in a lab-based role.

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