PBPK Director

Job IntroductionWe are looking for:To continue our growth as a premier Contract Research Organisation, we are looking to recruit a PBPK leader to join our organisation. In this new global role, you will lead on delivery of PBPK business through provision of PBPK modelling and simulation science and strategy from projects in the discovery phase through to the clinic.  Through building further capability and devising business plans you will have opportunity  to lead on the delivery of PBPK across Pharmaron.  You will work primarily alongside UK Drug Discovery and China based teams but also collaborate with other business units to offer expanded integrated services.This role will further develop overall Pharmaron capabilities and enhance the reputation of Pharmaron with its scientific and commercial stakeholders.At Pharmaron we offer:Vibrant and dynamic employment – we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and excitingOpportunities to develop your skills and yourself – our rapid growth brings greater opportunities for you to learn and grow fasterA great team where we all support each other – enjoy your work – after all you spend about a third of your time hereKey roles and responsibilities:Work with global DMPK Leadership Team to deliver PBPK business strategy for global Pharmaron including contracts, recruitment, software and business modelLead, design and deliver PBPK modelling and simulation contracts to support Pharmaron business units from Discovery through to clinical development. Work with global organisation to offer PBPK modelling as an integrated service to various business lines.Use own expertise in addition to providing mentoring, training and support ensuring PBPK contracts can be delivered to a high standard and in a timely mannerBuild the reputation of Pharmaron in PBPK through publications, conference/webinar presence and working with BD & marketing.Troubleshoot and overcome problems in projects across the Pharmaron organization through use of own technical knowledge and experience Deliver clear presentations on plans, data and achievements to external partners and internal stakeholders.Requirements:Extensive and demonstrable experience in conducting PBPK modelling and simulation work to support the pharmaceutical industry in discovery and/or development activities with solid understanding of related disciplinesDemonstrated impact in scientific leadership applied to drug discovery and development gained from at least 10 years experience in the industry Ability to  devise and execute strategy, influences takeholders and  ability to adapt working style to suit different cultures and partner expectationsMinimum BSc level qualification in a relevant scientific discipline with a history of publication and presentations.In depth knowledge and experience of PBPK principles, application and software packages such as Gastroplus, SimCYPExcellent understanding of how physicochemical properties relate to drug behaviourSignificant knowledge of approaches and capabilities to conduct human PK and dose prediction Robust understanding and experience of in vitro-in vivo extrapolation approaches across ADME principlesDemonstrated understanding of drug developability properties and risk mitigation strategies, for example DDI, formulation assessmentDynamic personality with a demonstrable passion for innovation and problem-solving who is comfortable working as an individual and collaboratively.Excellent communication, both written and oral, with the ability to influence and to effectively communicating across multiple formats including face to face and virtual project team environmentsOur Company: “We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world’s leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges”.We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We take pride in our professionalism and commitment to always deliver our very best work.We offer a competitive salary and a progressive and comprehensive suite of employee benefits.We offer state of the art working environment across our sites.We offer the opportunity for growth and development and will support funding for relevant training and development programmes.Why Should You Apply?This is an opportunity for you as PBPK leader to make a real impact in a highly scientific and dynamic environment, demonstrate leadership, ambition and the desire to drive forward and embed PBPK into the business.Continue to build and shape your career in an environment that sets and commits to the highest standards of DMPK science.To be part of a team who support each other, embrace and solve technical challenges and put excellence at the heart of all that we do.Pharmaron is a premier R&D service company supporting the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities having established diverse drug R&D service capabilities, ranging from synthetic, medicinal, and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry and isotopically labelled metabolism, chemical & pharmaceutical development to clinical development.  With operations in China, US and UK staffed by over 19,000 employees, Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan, and China.Single description (external)
Salary
Competitive

Job Reference
ukpharmaron/TP/79/215

Contract Type
Permanent Contract (Full-Time or Part-Time)

Closing Date
No Expiry Date

Job Category
Scientific (DMPK)

Division

Drug Discovery

Location
Hoddesdon, United Kingdom

Posted on
06 December, 2023