Principal Investigator

4 days ago

Newcastle upon Tyne, United Kingdom Green Life Science Full time

Lead Physician – LondonOverviewAn exciting opportunity is available for a senior medical professional to take a leadership role in the delivery of clinical trials involving various Therapy area's. The position is ideal for someone with prior Principal Investigator experience and a strong interest in mental health innovation. You’ll be working across dynamic, multi-disciplinary teams, guiding trials from early phases through to completion, while maintaining the highest standards in clinical care, compliance, and operational delivery.Role FocusThe successful candidate will be responsible for safeguarding participant wellbeing, ensuring trial integrity, and upholding compliance with all relevant clinical regulations and best practices. In this role, you’ll help shape the future of research in an evolving area of mental health treatment.Key Duties and ResponsibilitiesTake full responsibility for the medical conduct of clinical studies as the lead investigatorEnsure all research activities comply with Good Clinical Practice (GCP) guidelines and regulatory standardsConduct eligibility assessments, safety evaluations, and clinical reviews throughout the study lifecycleMake appropriate clinical decisions regarding patient inclusion, dosing readiness, and follow-up careSupervise the reporting of any adverse or serious adverse events and ensure timely communication with relevant oversight bodiesMentor and support clinical teams involved in research delivery, providing ongoing guidance and medical inputCollaborate effectively with operational teams, sponsors, and external research partnersReview and sign off on essential clinical documentation, including source notes and trial case report formsOversee the use, control, and accountability of investigational products and other study-related medicationsMonitor the collection and quality of structured clinical assessments and psychiatric rating scalesKeep up to date with developments in psychedelic research and relevant clinical guidelinesSkills and Experience RequiredMedical qualification with active professional registration and licence to practiseSpecialist accreditation or membership (e.g., psychiatry, internal medicine, or similar)Prior experience acting as Principal Investigator on clinical trialsSolid understanding of regulatory frameworks including GCP, FDA, EMA, and other global standardsPrevious involvement in psychiatric or CNS-focused studies preferredConfident in managing clinical risk and making sound medical decisionsProficient in clinical assessments and familiar with tools such as MINI, CAPS-5, or C-SSRSStrong communicator, capable of working with diverse teams and external stakeholdersComfortable with oversight of investigational products and protocol compliance

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