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Director HTA Biostatistics

1 month ago


London, United Kingdom Novartis Full time

Job Description Summary
We are in search of a Director/Senior Director, Health Technology Assessment (HTA) Biostatistics, with statistical expertise in HTA and Pricing and Reimbursement activities. This role offers the chance to provide statistical solutions to HTA problems. The successful candidate will work closely with International Value & Access and HEOR teams to shape ways of working for Joint Clinical Assessment in Europe to ensure high-quality deliverables.


Job Description


Our Development Team is guided by our purpose: to reimagine medicine to improve and extend people's lives. To do this, we are optimizing and strengthening our processes and ways of working. We are investing in new technologies and building specific therapeutic area and platform depth and capabilities - all to bring our medicines to patients even faster. We are seeking key talent, like you, to join us and help give people with disease and their families a brighter future to look forward to. Apply today and welcome to where we thrive together


The Role


200+ compounds in Novartis are supported by biostatisticians in 10+ sites around the globe. Biostatisticians transform clinical data into analyses that build the basis for making innovative drugs accessible for patients. They influence decision-making in cross-functional international teams from early to late phase drug development.


Come to an industry leader where you will lead implementation of modern and innovative trial/experimental designs, statistical models, analysis and data exploration methodologies at the project level. This role offers hybrid working, requiring 3 days per week in our London office.


Key Accountabilities:

  1. Accountable for strategic statistical input and influence into one or more projects (clinical development plan, integrated evidence generation strategy, publication strategy, market access strategy, pricing & reimbursement strategy).
  2. Lead implementation of efficient and innovative statistical methodology in HTA (indirect treatment comparison methods such as (network)-meta-analysis, population-adjusted methods, etc.), reimbursement activities, clinical trials, and observational research to accelerate patient access considering requirements across the globe (Europe, Asia Pacific and other geographies).
  3. Lead collaborations with Health Economics and Outcome Research, Market Access, and other strategic functions to drive quantitative decision making in assigned indications/program.
  4. Plan, prioritize and oversee project level activities and ensure efficient resource management within or across franchise and effective partnership with vendors.
  5. Support responses to payer requests and/or interactions. Actively contribute to internal and external scientific interactions with decision making agencies and healthcare professionals.
  6. Responsible for all statistical work, scientific and operational, in collaboration with cross-functional and cross-regional partners.
  7. Ensure quality, timely and consistency of statistical deliverables, organizational learning, and knowledge through consistent application of processes & best practices.
  8. Support selection of external vendors and oversee them for outsourced activities.
  9. Keep up to date with industry trends, advancements in HTA, and innovative statistical methodology (particularly in methods applicable to observational research area of HTA) to maintain proficiency in applying new and varied methods and to be competent in justifying methods selected.
  10. Communicate statistical findings and recommendations to non-statistical stakeholders in a clear and understandable manner.
  11. Develop and mentor biostatisticians on statistical methodologies and processes.

Your experience:

  1. PhD with 8+ years' experience preferred or MS with 12+ years' experience with a degree emphasis in in Statistics, Mathematics or equivalent quantitative field.
  2. Advanced knowledge of applying statistics (especially indirect treatment comparison methods such as (network)-meta-analysis, population-adjusted methods, etc.) and innovative approaches in experimental design and causal inference method.
  3. Expertise in HTA, reimbursement process and regulations, including key decision drivers and review processes for key international markets and strong understanding of regulatory authority processes, and drug development.
  4. Ability to manage parallel multiple projects in different therapeutic areas.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together?


Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse team's representative of the patients and communities we serve.


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Skills Desired:

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