Chief Scientific Officer

3 weeks ago


Bristol, Bristol, United Kingdom Gloo Full time

Chief Scientific Officer – AI-Driven Antibody Discovery

Location: Hybrid – UK/US

Salary: Competitive + Equity

A pioneering biotech start-up is seeking a Chief Scientific Officer (CSO) to lead the development of a cutting-edge biologics pipeline, leveraging AI-driven antibody discovery to transform drug development. This is an opportunity to take the helm in shaping the scientific strategy, working with a highly skilled team at the intersection of machine learning and biologics.

Why Join?

  • Be part of a high-growth biotech revolutionizing antibody drug discovery.
  • Lead the transition of AI-designed biologics from discovery to IND-ready assets.
  • Work with GPCRs and ion channels, focusing on target validation, antibody optimization, and developability.
  • Play a key role in securing investment and forming strategic partnerships with pharma and biotech companies.
  • A fast-paced, agile environment where you can shape the future of AI in antibody therapeutics.

The Role

As CSO, you will drive the scientific strategy, overseeing the entire biologics development pipeline from target selection through IND submission. You will work closely with the C-suite, investors, and external partners, ensuring scientific excellence and strategic execution.

Key Responsibilities:

Develop and execute a pipeline strategy from target selection (GPCRs & ion channels) to IND submission.

Transition AI-designed antibody candidates into preclinical and IND-ready biologics.

Leverage AI and machine learning for target validation, antibody optimization, and efficacy/tox prediction.

Establish credibility with investors, pharma, and strategic partners.

Manage collaborations, CDMOs, and preclinical model providers.

Provide scientific leadership and strategic direction to internal R&D teams.

About You

PhD in Biology, Biochemistry, Molecular Biology, or a related field.

15+ years of experience in antibody discovery, biologics development, and target selection.

Proven ability to integrate AI-driven approaches into drug discovery.

Strong leadership skills, with experience managing scientific teams.

Established track record in investor relations and pharma partnerships.

Expertise in preclinical development, IND submission, and regulatory strategy.

What's on Offer?

Competitive Salary + Stock Options

Flexible & Hybrid Working (UK/US Offices)

25+ Days Holiday + Public Holidays

Health Insurance & Gym Discounts

Home & Office Equipment Allowances

Referral Bonuses & Summer Fridays (extra time off)

If you're a visionary leader looking to make a real impact in AI-driven biologics, we want to hear from you Even if your experience isn't a perfect match, motivation and innovation matter most—let's have a conversation.


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