Senior Bioinformatics Scientist

1 week ago

Oxford, United Kingdom Warman O'Brien Full time

Senior Bioinformatician


Who are they?


I’m working with a stealth mode organisation who are an Oxford University spin off early-stage genetic therapy platform company. They’re advancing precision medicine by harnessing the power of protein isoforms, specifically focusing on treating neuromuscular diseases of high unmet needs. This company is backed by an established venture capital investor and have a clear mission to improve lives through genetic medicine.


Key responsibilities:

  • Collaborating closely with scientists and biologists internally and externally to design, implement and improve our bioinformatics capabilities including new workflows and tools required for target and drug discovery.
  • Establishing, implementing, and managing a robust and scalable bioinformatics data storage system.
  • Developing data storage policies to ensure data integrity, security, and compliance with industry regulations
  • Working independently to process and develop bioinformatics pipelines
  • Reporting results clearly to bench and dry lab collaborators and other partners and communicating results in wider team meetings


Essential Qualifications

  • A PhD in Computational Biology, Bioinformatics, Computer Science with relevant experience in transcriptomics analyses.
  • Significant experience with mammalian genomics and transcriptomics; Prior experience in human genomics
  • Experience with long read RNA sequencing data analysis
  • Experience with implementing NGS analysis pipelines for the following analyses is a plus: single-cell RNA sequencing, differential gene expression and splicing analysis/ isoform discovery
  • Highly proficient in computing languages including R and/or Phyton and use of statistical tools for biological interpretations.
  • Ability to work in a fast-paced environment and deliver high quality data within deadline-driven workflows.


What's in it for you?

  • The opportunities to work alongside a talented and passionate team of researchers and industry experts.
  • Access to cutting-edge laboratory facilities and state-of-the-art gene therapy technology.
  • Competitive salary/ compensation package.
  • A healthy work-life balance.
  • The chance to be part of a genetic medicine revolution that can change lives.
  • The opportunity to be an early team member of an exciting new biotech start-up.

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