Postdoctoral Research Associate: Understanding the Structure and Function of Microclots in Disease States

3 weeks ago


Liverpool, Liverpool, United Kingdom University of Liverpool Full time

We are looking for an enthusiastic Postdoctoral Research Associate to join the team of Professor Cheng-Hock Toh on an NHS founded project.

The successful applicant with an interest in studying the structure and function of large complexes that relate to blood coagulation in critical illness will join a world leading multidisciplinary team that includes clinicians and basic scientists that aims to carry out bench to bedside research. Our main research focus utilizes our strong clinical links within the NHS to improve patient care in both haematology and critically illness, particularly in intensive care units (ICU). This research utilizes basic molecular, cellular and protein biochemical methodologies to comprehensively undertake bench-to-bedside research.

With the collaboration of Chemistry Departments, the microclots will be characterised firstly by scanning and transmission electronic microscopy. In partnership with the Cryo-EM team of Leeds University, the successful applicant will also be able to try to solve the 3D structure of histone H4-fibrinogen microclots.

You will have a PhD in Biochemistry or related discipline. Laboratory experience with protein biochemistry, structural biology, EM or Cryo-EM would be advantageous.

The post is available for 3 years fixed term. Start date as near as possible to 1 July 2024.

Job Ref: Closing Date: 19 May 2024

For full details and to apply online, please visit:

£38,205 to £44,264 pa



  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    A postdoctoral research associate is sought by the Glyco-oncology Research Group in the Department of Biochemistry, Cell and Systems Biology.You will undertake a translational project funded by MRC and the Wellcome Trust to investigate effects of new therapeutic agents on tumour growth and metastasis using in vivo and ex vivo models. You will also be...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    We are seeking an enthusiastic individual to develop new instruments at the interface between engineering and life sciences. The project aims to translate research on the role amyloid microclots in long covid into a diagnostic instrument that can be used to aid diagnosis. The project is a collaboration between the Department of Electrical Engineering and...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    Applications are invited for a Postdoctoral Research Associate position in the Department of Mathematics at the University of Liverpool. You will work under the supervision of Dr Andreas Alpers. The position is funded by Dr Alpers¿ E.P.S.R.C New Investigator Award project "Optimal Grain Diagrams: Mathematical Analysis and Algorithms". You will contribute to...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    The Department of History seeks to recruit a Postdoctoral Research Associate as part of the Fritz-Thyssen-Foundation Award project "Massacre and the Law. Atrocity, The Holy Roman Empire, and the Thirty Years War". This interdisciplinary project investigates how the escalation of excessive violence and atrocity during the Thirty Years War affected normative...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    The Department of History seeks to recruit a Postdoctoral Research Associate as part of the Fritz-Thyssen-Foundation Award project "Massacre and the Law. Atrocity, The Holy Roman Empire, and the Thirty Years War". This interdisciplinary project investigates how the escalation of excessive violence and atrocity during the Thirty Years War affected normative...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    We are seeking a Post-Doctoral Research Associate with practical experience in biochemical and biophysical methods of protein interaction analysis. We are looking for an enthusiastic and ambitious researcher interested in using state-of-the-art structural, biochemical and mechanobiological approaches to explore the mechanosensitive links between the...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    Fixed term post from 1st July 2024 – 30th November 2027We are seeking an experienced and motivated Postdoctoral Research Associate (PDRA) to work within the Department of Pharmacology and Therapeutics in collaboration with the Liverpool Centre of Alcohol Research and the Liverpool University Hospital Foundation NHS Trust. You will have expertise in health...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    We are seeking a Post-Doctoral Research Associate with practical experience in biochemical and biophysical methods of protein interaction analysis. We are looking for an enthusiastic and ambitious researcher interested in using state-of-the-art structural, biochemical and mechanobiological approaches to explore the mechanosensitive links between the...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    We are seeking to recruit a postdoctoral researcher in inorganic materials synthesis to work in a multidisciplinary Engineering and Physical Sciences Research Council Programme Grant team to discover new materials for Next Generation Photovoltaics.You should have a PhD in Chemistry, Physics or Materials Science, a strong publication track record and a...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    This is an exciting opportunity for a post-doctoral scientist to contribute to the development of recommendations for sustainable parasite control in UK cattle as part of the BBSRC-funded BRACE project (Biosecurity and Roundworm Advice for Cattle Enterprises) by developing a mathematical model of nematode transmission between holdings. You will form part of...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    A postdoctoral research associate position is available in our QUASAR Group, focusing on the design and optimization of enhanced structures for ultra-compact dielectric laser accelerators and novel carbon nanotube (CNT)-based structures.Recent advances in fabrication technology enable the production of very compact, layered structures with controllable...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    The Hadronic Matter Group of the Physics Department is seeking a Postdoctoral Research Associate to support its STFC-funded Electron Ion Collider R&D programme, which aims to develop new technologies for future particle vertexing and tracking silicon detectors.In close collaboration with other UK universities and STFC laboratories, as well as in partnership...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    This is an exciting opportunity for a talented, organised and highly motivated postdoctoral scientist to join the Perinatal Pharmacology Group on a Wellcome Trust funded translational research programme. The overarching aim is to develop an integrated, physiologically based, multiscale platform to humanise preclinical assessment of fetal drug exposure and...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    We are recruiting a Postdoctoral Research Associate in Molecular Virology to join the laboratory of Professor. Julian Hiscox. The research in the laboratory is focused on human coronaviruses (SARS-CoV-2, MERS-CoV and seasonal human coronaviruses). This project fits within our general theme of viral evolution and host interactions in the presence and absence...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    This is an exciting opportunity for a talented, organised and highly motivated individual to join the team as a Postdoctoral Research Associate (PDRA) on an MRC funded translational research project in the Department of Eye and Vision Sciences at the University of Liverpool. This multidisciplinary project will develop a novel cell bandage to treat persistent...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    This is an exciting opportunity for a talented, organised and highly motivated individual to join the team as a Postdoctoral Research Associate (PDRA) on an MRC funded translational research project in the Department of Eye and Vision Sciences at the University of Liverpool. This multidisciplinary project will develop a novel cell bandage to treat persistent...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    A Postdoctoral Research Associate (PDRA) position is available immediately in the department of Chemistry, as part of the research groups of Professor Andrew Cooper FRS and Professor Anna Slater.We are looking to recruit a PDRA to join a collaborative project funded by the UK Atomic Energy Authority in partnership with Atkins and the National Physical...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    The group of Professor Andy Jones is looking for a bioinformatics Postdoctoral Research Associate to join the ¿PanOryza¿ project (UK-USA-Philippines), aimed with creating pan gene, protein and pathway set for *Orzya sativa* (rice) for 16 platinum standard genomes, covering major domesticated varieties and ~25 wild relatives. You will develop software for...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    A full-time postdoctoral position in musculoskeletal pathology of ageing is available in the Department of Musculoskeletal and Ageing Science at the University in the Osteoarthritis group headed by principal investigator Dr Blandine Poulet, in collaboration with the Engineering Biomechanics Group in the Faculty of Science and Engineering lead by Professor...


  • Liverpool, Liverpool, United Kingdom University of Liverpool Full time

    A full-time postdoctoral position in musculoskeletal pathology of ageing is available in the Department of Musculoskeletal and Ageing Science at the University in the Osteoarthritis group headed by principal investigator Dr Blandine Poulet, in collaboration with the Engineering Biomechanics Group in the Faculty of Science and Engineering lead by Professor...