Research/ Senior Scientist, Antibody Humanisation

3 weeks ago


Slough, Slough, United Kingdom UCB Full time

Make your mark for patients

UCB's Antibody Discovery and Optimisation Department are looking for a Research / Senior Scientist with a passion for delivering innovative, antibody- based therapeutics for patients suffering with serious disease.

About the role

As a member of the Antibody Humanisation and Engineering team at UCB you will cover various aspects of the antibody development process, including antibody engineering and humanisation design using structural information, antibody cloning and generation of expression plasmids and purification and characterisation of the biophysical properties of candidate antibody molecules.

Who you'll work with

Successful candidates will join a small but impactful team who have a passion for scientific research.

What you'll do

  • Design and engineer therapeutic antibodies for projects across the UCB portfolio
  • Clone and express antibodies in mammalian cell culture (CHO and HEK-293 cells) to provide material for assessment
  • Use structural insights and computational methods and optimise antibody candidate sequences to improve their eligibility for development
  • Analyse and interpret data to design next experiments
  • Collaborate with internal UCB teams to ensure work is carried out to a high standard and achieving agreed timelines

Interested? For this role we're looking for the following education, experience and skills

  • BSc in a relevant scientific discipline (PhD desirable)
  • A background in molecular biology, protein / antibody expression in mammalian cell culture and/ or structural biology
  • Experience in antibody cloning/ engineering or biophysical characterisation
  • An inquisitive and innovative nature with the desire for continuous learning
  • Excellent communication skills to collaborate with stakeholders
  • Proactive and positive mindset with a passion for scientific research

Are you ready to 'go beyond' to create value and make your mark for patients? If this sounds like you, then we would love to hear from you

About us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.

Why work with us?
At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.

UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on on EMEA- Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.



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