Assay Development Scientist
3 weeks ago
A rapidly growing biotechnology company is seeking an Assay Development Scientist to drive the end-to-end development of single-molecule assay kits for pharmaceutical research applications. This is a hands-on, cross-functional position bridging product design and manufacturing — ideal for a scientist who combines technical depth with practical experience in developing robust, scalable assay products. You’ll convert product specifications into validated, manufacturable kits optimized for advanced single-molecule detection platforms. The remit spans feasibility assessment, experimental design, optimization, validation, and technology transfer, ensuring each product meets rigorous scientific and operational standards. Key Responsibilities Translate product specifications into experimental objectives and development plans. Assess assay feasibility, component compatibility, and manufacturability within single-molecule workflows. Develop and optimize fluorescence-based assays (e.g. smFRET, FCS, FCCS). Design and execute analytical validation studies for sensitivity, precision, and reproducibility. Define and implement quality control criteria and documentation for manufacturing transfer. Collaborate closely with Manufacturing, Quality, and Product Management to ensure seamless scale-up. Provide technical data and support for pharmaceutical customer applications. Essential Skills and Experience PhD (or equivalent industry experience) in Biophysics, Biochemistry, Chemistry, or a related discipline. Proven track record in assay development, optimization, and validation for industrial or pharmaceutical use. Experience translating research assays into reproducible kit formats. Strong experimental design and quantitative analytical skills. Excellent documentation and communication abilities. Proven success managing cross-functional development projects. Preferred Hands-on experience with single-molecule fluorescence techniques (smFRET, FCS, FCCS). Expertise in biochemical assay development for proteins, nucleic acids, or complex molecular systems. Familiarity with pharmaceutical assay development, kinetics, or screening. Exposure to design-for-manufacture, GLP, or ISO 13485-aligned frameworks. The Offer Competitive salary Share options 4% employer pension contribution 26 days annual leave On-site, collaborative R&D environment Opportunity to shape a new generation of high-performance molecular assays for the pharmaceutical industry
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Product Manager – Assay Kits
2 weeks ago
Sheffield, United Kingdom Exciting Instruments Limited Full timeLocation: Sheffield, UKOn-site preferred; hybrid considered for exceptional candidates About the Role The Product Manager (Assay Kits) is responsible for defining, prioritising, and delivering Exciting Instruments’ portfolio of in-solution single-molecule assay kits for pharmaceutical and life sciences customers. This role connects scientific, commercial,...
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Data Scientist
1 week ago
Sheffield, United Kingdom HSBC Full timeTechnology teams in the UK work closely with our global businesses to help design and build digital services that allow our millions of customers around the world to bank quickly simply and securely. They also run and manage our IT infrastructure data centres and core banking systems that power the worlds leading international bank. Our multi-disciplined...
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Data Scientist
4 weeks ago
Sheffield, United Kingdom MBN Solutions Full timeData Scientist – Media - London - up to £90kAre you a pro at building and deploying ML models?Are you tired of just tinkering with the latest tech without actually making a real impact on business problems?Maybe you'd like to join our team of 50 like-minded ML scientists and engineers who work with zero red tape to create practical solutions that actually...
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Biomedical Scientist Practitioner
6 days ago
Sheffield, United Kingdom NHS Blood and Transplant Full timeJob Summary At NHSBT we stand for hope. We stand for life. We stand for helping people do something extraordinary, saving and improving the lives of others. Are you ready to play your part? We have an exciting opportunity for a HCPC registered Biomedical Scientist with post graduate training to join our Histocompatibility and Immunogenetics (H&I) Laboratory....
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Biomedical Scientist
2 days ago
Sheffield, United Kingdom NHS Blood and Transplant Full timeJob Summary Please note that the working hours for this post will be covering the 3 x shifts in the department (after training if required). Early shift – 07 : 30 to 15 : 30, Day shift – 08 : 30 to 16 : 30 and Late shift – 11 : 30 to 19 : 30. You will also be required to participate in the departments on call rota, following appropriate training. The...
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Data Scientist
4 weeks ago
Sheffield, United Kingdom HSBC Full timeTechnology teams in the UK work closely with our global businesses to help design and build digital services that allow our millions of customers around the world, to bank quickly, simply and securely. They also run and manage our IT infrastructure, data centres and core banking systems that power the world's leading international bank. Our multi-disciplined...
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Data Scientist
4 weeks ago
Sheffield, United Kingdom HSBC Full timeTechnology teams in the UK work closely with our global businesses to help design and build digital services that allow our millions of customers around the world, to bank quickly, simply and securely. They also run and manage our IT infrastructure, data centres and core banking systems that power the world's leading international bank. Our multi-disciplined...
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Data Scientist- 6 Month Internship
1 week ago
Sheffield, United Kingdom Twinkl Full time**Location**:Permanently located in the UK** (option of UK remote working or office working at Sheffield HQ)** **Annual Salary**: £21,255 pro rata **Contract**: 6-month internship, with possible permanent position opportunity **Visa Sponsorship**:Not available. All applicants must have the Right to Work in the UK for the duration of the...
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Junior Software Developer
1 week ago
Sheffield, Sheffield, United Kingdom Bruker Corporation Full time £30,000 - £50,000 per yearOverviewBruker is enabling scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker's high performance scientific instruments and high value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular, and microscopic levels. In close cooperation...
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Sheffield, United Kingdom NHS Blood and Transplant Full timeA national healthcare organization in the UK seeks a Biomedical Scientist to perform crucial laboratory tests related to organ transplants and blood transfusions. The successful candidate will support new staff and manage blood samples, working flexible shifts and potentially with on-call responsibilities. Candidates must be HCPC registered and possess a...