Current jobs related to Senior Scientist - Cambridge, Cambridgeshire - AstraZeneca UK

  • Senior Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Senior Formulations ScientistYou are a project leading formulations scientist with a deep understanding of nanoparticle design for drug delivery systems. You have designed nanoparticles that deliver gene therapies (e.g. RNAs, DNAs, or even AAVs).Why have you developed this expertise? Is it to design therapies that can penetrate biological barriers (e.g. the...

  • Senior Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Senior Formulations ScientistYou are a project leading formulations scientist with a deep understanding of nanoparticle design for drug delivery systems. You have designed nanoparticles that deliver gene therapies (e.g. RNAs, DNAs, or even AAVs).Why have you developed this expertise? Is it to design therapies that can penetrate biological barriers (e.g. the...

  • Senior Scientist

    7 days ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Senior Formulations Scientist // Gene Therapy // Nanoparticle // Cambridge Unlock the Potential of Nanotherapies We are seeking a highly skilled Senior Formulations Scientist to join our team at Singular: Building Brilliant Biotechs. As a key member of our team, you will be responsible for designing and developing innovative nanoparticle-based drug...

  • Senior Scientist

    7 days ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Senior Formulations Scientist // Gene Therapy // Nanoparticle // Cambridge Unlock the Potential of Nanotherapies We are seeking a highly skilled Senior Formulations Scientist to join our team at Singular: Building Brilliant Biotechs. As a key member of our team, you will be responsible for designing and developing innovative nanoparticle-based drug...

  • Senior Scientist

    4 days ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Senior Formulations ScientistWe are seeking a highly skilled Senior Formulations Scientist to join our team at Singular: Building Brilliant Biotechs. As a key member of our research team, you will be responsible for designing and developing innovative nanoparticle formulations for gene therapy applications.Key Responsibilities:Design and develop nanoparticle...

  • Senior Scientist

    3 days ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Senior Formulations ScientistWe are seeking a highly skilled Senior Formulations Scientist to join our team at Singular: Building Brilliant Biotechs. As a key member of our research team, you will be responsible for designing and developing innovative nanoparticle formulations for gene therapy applications.Key Responsibilities:Design and develop nanoparticle...

  • Senior Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job Title: Senior ScientistCompany: Singular: Building Brilliant BiotechsJob Summary:We are seeking a highly experienced Senior Scientist to join our team at Singular: Building Brilliant Biotechs. As a Senior Scientist, you will play a key role in leading our formulations team and contributing to the development of innovative nanotherapies.Key...

  • Senior Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job Title: Senior ScientistCompany: Singular: Building Brilliant BiotechsJob Summary:We are seeking a highly experienced Senior Scientist to join our team at Singular: Building Brilliant Biotechs. As a Senior Scientist, you will play a key role in leading our formulations team and contributing to the development of innovative nanotherapies.Key...

  • Senior Scientist

    1 week ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job OpportunitySingular: Building Brilliant BiotechsWe are seeking a highly skilled Senior Scientist to join our team at Singular: Building Brilliant Biotechs. As a leading biotech company, we are dedicated to developing innovative nanotherapies that have the potential to revolutionize the field of gene therapy.About the RoleWe are looking for a seasoned...

  • Senior Scientist

    1 week ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job OpportunitySingular: Building Brilliant BiotechsWe are seeking a highly skilled Senior Scientist to join our team at Singular: Building Brilliant Biotechs. As a leading biotech company, we are dedicated to developing innovative nanotherapies that have the potential to revolutionize the field of gene therapy.About the RoleWe are looking for a seasoned...

  • Senior RNA Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Senior RNA Scientist OpportunityWe are seeking a highly experienced RNA scientist to lead our team in the development of innovative nucleic acid therapies. As a Senior RNA Scientist, you will be responsible for designing and formulating RNA-based therapeutics that can overcome difficult biological barriers.The ideal candidate will have a deep understanding...

  • Senior RNA Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Senior RNA Scientist OpportunityWe are seeking a highly experienced RNA scientist to lead our team in the development of innovative nucleic acid therapies. As a Senior RNA Scientist, you will be responsible for designing and formulating RNA-based therapeutics that can overcome difficult biological barriers.The ideal candidate will have a deep understanding...

  • Senior Pharmacovigilance Scientist

    1 day ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Senior Scientist - CNS Translational ResearchWe are seeking a highly skilled Senior Scientist to lead our CNS translational research efforts. As a key member of our team, you will be responsible for developing complex 'in-vitro' CNS disease models to discover gene therapies.Our team is working with a Cambridge-based start-up that has announced a large...

  • Senior Pharmacovigilance Scientist

    24 hours ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Senior Scientist - CNS Translational ResearchWe are seeking a highly skilled Senior Scientist to lead our CNS translational research efforts. As a key member of our team, you will be responsible for developing complex 'in-vitro' CNS disease models to discover gene therapies.Our team is working with a Cambridge-based start-up that has announced a large...

  • Senior RNA Scientist

    1 day ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job OpportunitySenior Scientist - RNA TherapeuticsWe are seeking a highly skilled Senior Scientist to join our team at Singular: Building Brilliant Biotechs. As a Senior Scientist, you will be responsible for leading RNA drug delivery projects, leveraging your expertise in nucleic acid chemistry and formulations to design targeted therapies for patients with...

  • Senior RNA Scientist

    1 day ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job OpportunitySenior Scientist - RNA TherapeuticsWe are seeking a highly skilled Senior Scientist to join our team at Singular: Building Brilliant Biotechs. As a Senior Scientist, you will be responsible for leading RNA drug delivery projects, leveraging your expertise in nucleic acid chemistry and formulations to design targeted therapies for patients with...

  • Senior Research Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job Title: Research Scientist/Senior Research ScientistAbout the Role:We are seeking a highly skilled Research Scientist or Senior Research Scientist to join our team at Singular: Building Brilliant Biotechs. As a key member of our research team, you will be responsible for designing and developing novel nanoparticle-based drug delivery systems for the...

  • Senior RNA Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job DescriptionSenior RNA Scientist // Drug Delivery // Nanoparticle // CambridgeYou are a project leading RNA scientist with a deep understanding of nucleic acid chemistry, RNA drug delivery, formulations, and RNA therapeutics.Why have you developed this expertise? Is it to design targeted therapies for patients suffering from real unmet need?We are working...

  • Senior RNA Scientist

    2 weeks ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job DescriptionSenior RNA Scientist // Drug Delivery // Nanoparticle // CambridgeYou are a project leading RNA scientist with a deep understanding of nucleic acid chemistry, RNA drug delivery, formulations, and RNA therapeutics.Why have you developed this expertise? Is it to design targeted therapies for patients suffering from real unmet need?We are working...

  • Senior RNA Scientist

    3 days ago

    Cambridge, Cambridgeshire, United Kingdom Singular: Building Brilliant Biotechs Full time

    Job OpportunitySenior Scientist - RNA TherapeuticsWe are seeking a highly skilled Senior Scientist to join our team at Singular: Building Brilliant Biotechs. As a Senior Scientist, you will be responsible for leading the development of RNA therapeutics and nanoparticle formulations.About the RoleThis is an exciting opportunity to work with a rapidly growing...

Senior Scientist

3 months ago

Cambridge, Cambridgeshire, United Kingdom AstraZeneca UK Full time
Location - Cambridge DISC
Competitive salary and benefits package
Introduction to role:

Join our Biopharmaceuticals R&D team as a Senior Scientist, where you will be responsible for the operation of single-use bioreactor systems to produce recombinant proteins. You will also be involved in the further development and improvement of protein expression technologies, including cell line engineering. This is a great opportunity to be part of a team that follows the science unlike anywhere else, pushing the boundaries and celebrating both successes and failures along the way.

As a Senior Scientist, you will have a hands-on laboratory role as part of a cross-functional team. Your responsibilities will include plasmid DNA production in microbial systems, routine maintenance/passage of mammalian cell cultures for bioreactor inoculum generation, and maintaining and operating bench-scale and large-scale bioreactor systems. You will also participate in the development of new technologies and processes associated with protein expression and bioreactor processing.

The team

The Cell Culture & Fermentation Sciences (CCFS) department is made up of interdisciplinary teams collectively responsible for design, generation and selection of optimal manufacturing cell lines and processes for production of biologics. The Upstream Bioprocess Development team (UBD) within CCFS is responsible for generating recombinant proteins to support internal projects at all stages of Drug Discovery. The team also focuses on developing, optimizing and transferring well characterised scalable bioreactor processes for manufacture of recombinant proteins for use as human therapeutics.

Essential Skills/Experience:
  • Relevant university degree or equivalent experience (e.g., BSc/MSc/PhD) in life science, biochemical engineering or bioprocessing related subject area, with relevant industrial experience.
  • Experience in plasmid DNA production in microbial systems and molecular biology related techniques.
  • Experience in mammalian cell culture and protein expression in an industrial environment (CHO and/or HEK cell culture preferred).
  • Developing and troubleshooting mammalian expression systems as well as addressing protein expression issues.
  • Good problem-solving skills through formal channels and informal networks.
  • An adaptable teammate and leader capable of working to tight deadlines and exacting standards.
  • Enthusiastic, flexible and willing to learn.
  • High level of attention to detail.
  • Proactive communicator.
  • Good organisational and planning skills.

    Desirable Skills/Experience:
    • Experience in cell engineering.
    • Experience with bioreactor systems for mammalian suspension cell culture and/or microbial systems (bench scale to large scale).
    • Experience in the use of data science tools for the investigation and design of bioprocesses e.g., JMP / Design-Expert.

      When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. This is a lab based role with five days per week in the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
      Why AstraZeneca?
      At AstraZeneca, we are committed to making a difference. We have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. It's our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before. We work seamlessly as one, expanding our horizons and uniting the best from academia, biotechs and the industry. It's by coming together and using our diverse, global knowledge that we can create the greatest and swiftest impact on disease.
      Ready to make a difference? Apply today and join our team
      We encourage your application by 28th May 2024.
      AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.