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Principal Computational Biologist

3 months ago


Camden Area, Greater London, United Kingdom TEC Partners - Technical Recruitment Specialists Full time
Principal Computational Biologistn£75-90,000 salary DOEnMostly remote (must be UK resident and able to commute to London once or twice a month)nFull-time, permanent

Principal Computational Biologist Profile


We are looking for an exceptional Principal Computational Biologist to join their growing team on an exciting journey to support the development of advanced therapeutics addressing critical healthcare challenges.


You will lead advanced modelling methods, with a focus on generating novel target recommendations, validating them in models, and translating them into therapeutics.


Principal Computational Biologist key responsibilities:
– Lead the 'advanced modelling' workstreams, and be the point of contact and a role model for advanced modelling within the company.n– Maintain strong domain knowledge of leading 'omic and 'big data' computational methodsn– Drive experimental design & modelling of phenotyping and/ or omics data in close collaboration with wet-lab scientists.n– Work as a member of cross-functional teams bringing together best-in-class Drug Discovery, Drug Development, Product & Project Management capabilities.n– Routinely use Python/R for data analyses, in particular data wrangling, modelling and visualisation.n– Develop solutions to increase automation, reliability and scalability of our data processing pipelines and workflows.n– Lead, co-develop, and run pipelines in a cloud computing environment. Maintain progress in personal and professional development to better domain, technical, and professional skills.n– Contribute to documenting processes and code in the form of SOPs.n– Present research updates to project teams and to the management team.n– Contribute to training initiatives to foster a data-driven culture.

Principal Computational Biologist Qualifications & Experience:


Requiredn– PhD in computational biology or related PhDn– Experience delivering results in a fast-paced environment (biotech / pharma exposure would be an advantage)n– Strong experience in developing and modifying statistical (and ML) models of 'omics datasets for biological interpretation and actionable insightsn– Strong experience with experimental design, exploratory data analysis, reporting and visualisation of data.n– Experience in leading projects involving multiple stakeholders, end-to-end.

Desirablen– Experience in leading people and delivering through othersn– Experience with pipelines / reproducible scientific workflows development

Skills & Competencies


Requiredn– Deep understanding of human biology beyond the statistical/ML models being developedn– Good knowledge with rapidly prototyping, writing and maintaining Python and/or R code, harnessing statistical tools for biological interpretations.

n– Embracing change in a start-up environment

Desirablen-Familiarity with project management toolsn-Familiarity with Githubn-Familiarity with imaging MLn-Familiarity with cloud computing (AWS)


If this role sounds of interest, and you're looking to change the face of therapeutics and deliver meaningful change, then please apply right away to be considered.