Post-doc

1 week ago


Saffron Walden, Essex, United Kingdom Wellcome Sanger Institute Full time
Computational Postdoctoral Fellow - single-cell genomics in the Haniffa group

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity's greatest challenges.

The Cellular Genetics Programme is seeking a Postdoctoral Fellow to work on iPSC derived organoid datasets in the Haniffa Group .

The Programme is focused on cell-atlasing and aims to map tissues and organoids by combining single-cell transcriptomics, spatial genomics and computational methodologies to build full-transcriptome three-dimensional (3D) models of cells in their tissue context.

Muzlifah Haniffa is a dermatologist pioneering the applications of single cell genomics technologies to understand human development, tissue homeostasis, immunity and disease pathogenesis.

A major research goal of her laboratory is to decode the development and functional maturation of the human immune system and whole embryo development.

The Haniffa Group's research within the Cellular Genetics Programme applies disruptive cutting-edge single cell and spatial genomics techniques to study human development and adult healthy and diseased tissues.

The group is a diverse mixture of wet and dry lab researchers and clinicians and collaborates closely with leading teams in single cell and spatial biology including Sarah Teichmann, Fabian Theis and Mohammad Lotfollahi.

You will be closely interacting with the wet lab team, driving organoid development by generating large-scale atlases, identifying key regulatory mechanisms, and perturbing them in silico thereby actively promoting hypothesis testing and translational research.

You understand key concepts in genomics, data processing and high-throughput data analysis.

You will ideally have experience in the management and analysis of very large data sets, using or developing statistical/machine-learning methods for the analysis of large-scale data sets.

PhD in relevant subject area, or on track to be awarded your PhD within 6 months of starting the role
Proven ability to deliver research projects
o Ability to analyse and interpret data with strong quantitative/computational skills
Foster an inclusive culture where all can thrive and diversity is celebrated

Contract: 3 years

We recognise that there are many benefits to Hybrid Working; including an improved work-life balance, with more focused time, as well as the ability to organise working time so that collaborative opportunities and team discussions are facilitated on campus.

The hybrid working arrangement will vary for different roles and teams.

The nature of your role and the type of work you do will determine if a hybrid working arrangement is possible.


Equality, Diversity and Inclusion:

We have a supportive culture with the following staff networks, LGBTQ+, Parents and Carers, Disability and Race Equity to bring people together to share experiences, offer specific support and development opportunities and raise awareness.

The networks are also a place for allies to provide support to others.
We are proud to deliver an awarding campus-wide employee wellbeing strategy and programme.

The Technician Commitment aims to empower and ensure visibility, recognition, career development and sustainability for technicians working in higher education and research, across all disciplines.

Every year the Wellcome Sanger Institute supports the visits of dozens of overseas researchers from across the globe to the Genome campus to collaborate, share insights and to undertake ground-breaking scientific research.

Our reliable in-house service provides expert advice and guidance to support current and prospective staff, and visitors at various points of their journey.

We are able to provide guidance through your entire journey, from initial visa application through to extensions and applications of Indefinite Leave to Remain, the service is proud to support your personal applications and those of your dependants and family members.

Computational Postdoctoral Fellow - single-cell genomics in the Haniffa group
We are a world-leading genomics research institute. Our work helps improve human health and understand life on Earth.
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