PhD Studentship: Building the Vertebrate Spine: The Neck to Thorax Transition

Primary Supervisor: Professor Andrea Münsterberg Segmentation of the main body axis is a fundamental and conserved feature of all vertebrate embryos. It results in the metameric organization of the vertebral column and its associated muscles, nerves, and blood vessels. The vertebral column is produced by somites, transient aggregates of cells generated by...

Primary Supervisor: Professor Andrea Münsterberg Segmentation of the main body axis is a fundamental and conserved feature of all vertebrate embryos. It results in the metameric organization of the vertebral column and its associated muscles, nerves, and blood vessels. The vertebral column is produced by somites, transient aggregates of cells generated by...

Primary supervisor - Dr Fred Warren The infant gut is a complex, constantly adapting ecosystem which shows distinct shifts as a consequence of introducing solid foods, which can have lifelong health impacts. An important nutrient in weaning foods is starch, a key dietary component in the adult diet. The genus Bifidobacterium has several adaptations making it...

Primary supervisor - Dr Fred Warren The infant gut is a complex, constantly adapting ecosystem which shows distinct shifts as a consequence of introducing solid foods, which can have lifelong health impacts. An important nutrient in weaning foods is starch, a key dietary component in the adult diet. The genus Bifidobacterium has several adaptations making it...

Primary supervisor - Dr Fred Warren The infant gut is a complex, constantly adapting ecosystem which shows distinct shifts as a consequence of introducing solid foods, which can have lifelong health impacts. An important nutrient in weaning foods is starch, a key dietary component in the adult diet. The genus Bifidobacterium has several adaptations making it...

Primary supervisor - Dr Fred Warren  The infant gut is a complex, constantly adapting ecosystem which shows distinct shifts as a consequence of introducing solid foods, which can have lifelong health impacts. An important nutrient in weaning foods is starch, a key dietary component in the adult diet. The genus Bifidobacterium has several adaptations...

Primary supervisor - Professor Martin Warren This PhD opportunity is ideal for graduates in biochemistry or biomedical science with a keen interest in protein science and its application in developing new diagnostic tests and assays. Recently, the National Institute for Health and Care Excellence (NICE) issued comprehensive guidelines on diagnosing and...

Primary supervisor - Professor Martin Warren This PhD opportunity is ideal for graduates in biochemistry or biomedical science with a keen interest in protein science and its application in developing new diagnostic tests and assays. Recently, the National Institute for Health and Care Excellence (NICE) issued comprehensive guidelines on diagnosing and...

Primary supervisor - Professor Martin Warren  This PhD opportunity is ideal for graduates in biochemistry or biomedical science with a keen interest in protein science and its application in developing new diagnostic tests and assays. Recently, the National Institute for Health and Care Excellence (NICE) issued comprehensive guidelines on diagnosing and...

Primary Supervisor: Dr James Smith Cardiomyocytes are the muscle cells of the heart, responsible for the production of contraction forces. During development, cardiomyocytes withdraw from the cell-cycle and switch from proliferative, growth to non-proliferative, hypertrophic growth. It is becoming clear that the extracellular matrix molecules play a key role...

Primary Supervisor: Dr James Smith Cardiomyocytes are the muscle cells of the heart, responsible for the production of contraction forces. During development, cardiomyocytes withdraw from the cell-cycle and switch from proliferative, growth to non-proliferative, hypertrophic growth. It is becoming clear that the extracellular matrix molecules play a key role...

Primary supervisor - Dr Myriam Charpentier Nitrogen (N) acquisition is fundamental for plant growth. However, N is poorly available in soils, leading to extensive and costly chemical fertiliser applications. It is estimated that 50-70% of nitrogen-derived fertilizer provided to the soil is lost, giving rise to soil and water pollution as well as global...

Primary supervisor - Dr Myriam Charpentier Nitrogen (N) acquisition is fundamental for plant growth. However, N is poorly available in soils, leading to extensive and costly chemical fertiliser applications. It is estimated that 50-70% of nitrogen-derived fertilizer provided to the soil is lost, giving rise to soil and water pollution as well as global...

Primary supervisor - Dr Dmitry Ghilarov BackgroundNatural products forming the basis of our current medical arsenal are often difficult to synthesize, purify, or engineer. In recent years ribosomally-synthesized post-translationally modified peptides attracted attention as a flexible drug discovery platform. RiPPs are genetically encoded, made by the...

Primary supervisor - Dr Neil Hall Take-all is the most important root disease of wheat worldwide and is caused by the fungus Gaeumannomyces tritici. G. tritici belongs to an important group of grass-infecting pathogens including rice and wheat blast fungi (Magnaporthales, Ascomycota), but take-all of wheat is an understudied disease. Little is known about...

Primary supervisor - Dr Neil Hall Take-all is the most important root disease of wheat worldwide and is caused by the fungus Gaeumannomyces tritici. G. tritici belongs to an important group of grass-infecting pathogens including rice and wheat blast fungi (Magnaporthales, Ascomycota), but take-all of wheat is an understudied disease. Little is known about...

Primary supervisor - Dr Neil HallTake-all is the most important root disease of wheat worldwide and is caused by the fungus Gaeumannomyces tritici. G. tritici belongs to an important group of grass-infecting pathogens including rice and wheat blast fungi (Magnaporthales, Ascomycota), but take-all of wheat is an understudied disease. Little is known about how...

Primary supervisor - Dr Neil HallTake-all is the most important root disease of wheat worldwide and is caused by the fungus Gaeumannomyces tritici. G. tritici belongs to an important group of grass-infecting pathogens including rice and wheat blast fungi (Magnaporthales, Ascomycota), but take-all of wheat is an understudied disease. Little is known about how...

Primary supervisor - Dr Dmitry Ghilarov BackgroundThe acute problem of antimicrobial resistance incentivises us to develop innovative approaches to antibiotic discovery & production. Natural products that form the basis of our current medical arsenal are often difficult to synthesize, purify, or engineer. In recent years bioinformatically predicted peptide...

Primary supervisor - Professor Diane Saunders Wheat blast and rusts are fungal diseases that severely damage cereal production worldwide. During infection, these fungi secrete proteins into wheat plants to reprogramme host plant circuitry, supporting their own growth and development. A subset of effectors, termed avirulence factors (Avr), can be recognised...