Scientist 2 - CLD & USP in Wrexham

2 months ago


Wrexham, United Kingdom Ipsen Biopharm Ltd Full time

Ipsen is a growing and dynamic specialty-driven biopharmaceutical company focussed on innovation and specialty care.

The patient is at the heart of everything we do, and we also care for our employees because they are the ambassadors who truly make a difference. We attract and develop bold, agile and entrepreneurial individuals who take full ownership of their decisions, leaders drawn by a purpose to make a direct impact through their work in people’s lives, all of which is underpinned by our Ipsen Way of Being.

Main Tasks:

Assist in design, execution, analysis and documentation of experimental work related to cell line 

Executes research activities as applicable aligned with Research & Development pipeline. Design, execute and analyse experimental work related to cell line development including, vector construction, transfection/transformation, single cell cloning. Design, execute and analyse experimental work related to cell culture and fermentation process development, including developing robust inoculum expansion and fermentation processes suitable for clinical drug substance manufacture. Support manufacture of clinical drug substances.

Support intra- and inter-site cross functional interactions including external contracts - Collaborate with cross functional teams at departmental level to progress IPSEN’s biologics pipeline. - Collaborate with other site functions to support IPSEN’s biologics pipeline requirements. - Collaborate with third parties in order to progress BPD activities, including review of proposals, protocols and reports.

Support fit-for-purpose facilities; develop and maintain procedures, and documentation aligned with pipeline development needs - Support the implementation of new bioprocess technologies and support implementation of new bioprocess facilities/laboratories. - Ensure the system suitability of all laboratory equipment for the intended use. - Ensure that work is recorded and reviewed in appropriately controlled laboratory books, protocols or Batch Manufacturing Records.

Works within GMP, Regulatory and EHS requirements - Perform assigned tasks whilst, at all times, adhering to current GMP requirements (e.g. Annex 1 of EU GMP) for sterile medicinal products. - Report any compliance concerns to your line manager or the Quality Assurance Compliance team. - Work in a safe manner at all times and raise any Health and Safety concerns to your line manager or the EHS team. - Ensure all training is kept up to date and documented by adhering to training plan requirements, ensuring that you do not perform any tasks you are not trained to complete.

Education / Certifications:

Degree, Masters or PhD in appropriate scientific discipline or relevant experience.

Experience:

Minimum: Some proven work experience within cell line development or upstream process development team

Why Ipsen & Why Wrexham…

We are a business that is experiencing exponential growth and change, therefore presenting a wide range of opportunities and challenges

Major £multi-million investment in a New Drug Product Facility to increase the scale and capability of our Wrexham site, ultimately enhancing the products we develop for our customers

A fantastic culture and working environment with many long-serving employees

Huge commitment to Diversity & Inclusion - almost 50% of our top 160 leaders are women

A genuine focus on the environment and sustainability – our Wrexham site is powered by 100% renewable electricity

Competitive salaries and enhanced benefits package which includes annual bonus, generous pension scheme, wellness allowance and so much more.

Awarded ‘Best Workplaces’ and ‘Best Workplaces for Wellbeing’ status in the Large Organisations category, as well as ‘Best Workplaces for Women’ in 2023.

The pride of working for a company that directly impacts and changes lives for the better


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